NDC codes

FDA NDC Directory
Product NDC (as listed)63759-3049Labeler and product segments. Claims need a package NDC.
Product NDC at billing width63759-3049Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
63759-3049-1637593049011 VIAL in 1 CARTON (63759-3049-1) / 50 mL in 1 VIALMarketed from Jan 1, 2024

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Pemetrexed
Generic name (nonproprietary)
pemetrexed disodium
Active ingredients
Pemetrexed disodium hemipentahydrate — 500 mg/50mL
Dosage form
Injection
Route
Intravenous
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 215179
Marketing start
Listing expires
Other FDA classes
Folic Acid Metabolism Inhibitors (Mechanism)
Identifiers
Product ID 63759-3049_b0e3847a-fdcf-405c-823c-180fa8dad9c2SPL ID b0e3847a-fdcf-405c-823c-180fa8dad9c2SPL set ID fe432994-e61b-4a87-8c98-cc20b847d0feRxCUI 2637958, 2637966, 2637968UNII F4GSH45R4CUPC 0363759304912, 0363759304813, 0363759305018
Pharmacologic class
Folate Analog Metabolic Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N463759304901 followed by a unit qualifier and the quantity

Package 63759-3049-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Pemetrexed Injection is a folate analog metabolic inhibitor indicated: in combination with pembrolizumab and platinum chemotherapy, for the initial treatment of patients with metastatic non-squamous non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations. (1.1) in combination with cisplatin for the initial treatment of patients with locally advanced or metastatic, non-squamous NSCLC. (1.1) as a single agent for the maintenance treatment of patients with locally advanced or metastatic, non-squamous NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. (1.1) as a single agent for the treatment of patients with recurrent, m…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 215179

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 215179
ProductStrengthForm · routeLabelerProduct NDC
Pemrydi Rtupemetrexed disodiumPemetrexed disodium hemipentahydrate 100 mg/10mLInjectionIntravenousAmneal Pharmaceuticals LLC70121-2453
Pemrydi Rtupemetrexed disodiumPemetrexed disodium hemipentahydrate 500 mg/50mLInjectionIntravenousAmneal Pharmaceuticals LLC70121-2461
Pemrydi Rtupemetrexed disodiumPemetrexed disodium hemipentahydrate 1000 mg/100mLInjectionIntravenousAmneal Pharmaceuticals LLC70121-2462
Pemetrexedpemetrexed disodiumPemetrexed disodium hemipentahydrate 100 mg/10mLInjectionIntravenousShilpa Medicare Limited63759-3048
Pemetrexedpemetrexed disodiumPemetrexed disodium hemipentahydrate 1000 mg/100mLInjectionIntravenousShilpa Medicare Limited63759-3050

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