Pemetrexed (pemetrexed disodium) NDC 25021-260

NDC codes

FDA NDC Directory

Product NDC (as listed)25021-260Labeler and product segments. Claims need a package NDC.

Product NDC at billing width25021-0260Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
25021-260-10	25021026010	1 VIAL in 1 CARTON (25021-260-10) / 4.2 mL in 1 VIALMarketed from Dec 15, 2024

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Pemetrexed
Generic name (nonproprietary): pemetrexed disodium
Active ingredients: Pemetrexed disodium hemipentahydrate — 100 mg/4.2mL
Dosage form: Injection, Powder, Lyophilized, For solution
Route: Intravenous
Labeler: Sagent Pharmaceuticals
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 204890
Marketing start: Dec 15, 2024
Listing expires: Dec 31, 2027
Other FDA classes: Folic Acid Metabolism Inhibitors (Mechanism)
Identifiers: Product ID 25021-260_54581a8b-ea74-4481-9b05-a802a13dcd15SPL ID 54581a8b-ea74-4481-9b05-a802a13dcd15
Pharmacologic class: Folate Analog Metabolic Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N425021026010 followed by a unit qualifier and the quantity

Package 25021-0260-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

Other NDCs under ANDA 204890

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 204890
Product	Strength	Form · route	Labeler	Product NDC
Pemetrexedpemetrexed disodium	Pemetrexed disodium hemipentahydrate 500 mg/20mL	Injection, Powder, Lyophilized, For solutionIntravenous	Sagent Pharmaceuticals	25021-261
Pemetrexedpemetrexed disodium	Pemetrexed disodium hemipentahydrate 500 mg/20mL	Injection, Powder, Lyophilized, For solutionIntravenous	BluePoint Laboratories	68001-539
Pemetrexedpemetrexed disodium	Pemetrexed disodium hemipentahydrate 100 mg/4mL	Injection, Powder, Lyophilized, For solutionIntravenous	BluePoint Laboratories	68001-538
Pemetrexedpemetrexed disodium	Pemetrexed disodium hemipentahydrate 100 mg/4mL	Injection, Powder, Lyophilized, For solutionIntravenous	Qilu Pharmaceutical Co., Ltd.	67184-0503
Pemetrexedpemetrexed disodium	Pemetrexed disodium hemipentahydrate 500 mg/20mL	Injection, Powder, Lyophilized, For solutionIntravenous	Qilu Pharmaceutical Co., Ltd.	67184-0504