NDC codes

FDA NDC Directory
Product NDC (as listed)85534-0006Labeler and product segments. Claims need a package NDC.
Product NDC at billing width85534-0006Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
85534-0006-185534000601100 TABLET, EXTENDED RELEASE in 1 BOTTLE (85534-0006-1)Marketed from Jun 11, 2025
85534-0006-38553400060330 TABLET, EXTENDED RELEASE in 1 BOTTLE (85534-0006-3)Marketed from Jun 11, 2025
85534-0006-585534000605500 TABLET, EXTENDED RELEASE in 1 BOTTLE (85534-0006-5)Marketed from Jun 11, 2025
85534-0006-68553400060660 TABLET, EXTENDED RELEASE in 1 BOTTLE (85534-0006-6)Marketed from Jun 11, 2025
85534-0006-98553400060990 TABLET, EXTENDED RELEASE in 1 BOTTLE (85534-0006-9)Marketed from Jun 11, 2025

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Bupropion Hydrochloride
Generic name (nonproprietary)
bupropion hydrochloride
Active ingredients
Bupropion hydrochloride — 300 mg/1
Dosage form
Tablet, Extended release
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 077285
Marketing start
Listing expires
Other FDA classes
Dopamine Uptake Inhibitors (Mechanism)Increased Dopamine Activity (Physiologic effect)Increased Norepinephrine Activity (Physiologic effect)Norepinephrine Uptake Inhibitors (Mechanism)
Identifiers
Product ID 85534-0006_3745abec-26fc-d50e-e063-6294a90a037dSPL ID 3745abec-26fc-d50e-e063-6294a90a037dSPL set ID b4a1d3b8-afcf-47e3-96d3-469d8f408a31RxCUI 993557UNII ZG7E5POY8O
Pharmacologic class
Aminoketone

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N485534000601 followed by a unit qualifier and the quantity

Package 85534-0006-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

Bupropion hydrochloride extended-release tablets (XL) are an aminoketone antidepressant, indicated for: treatment of major depressive disorder (MDD) ( 1.1 ) prevention of seasonal affective disorder (SAD) ( 1.2 ) 1.1 Major Depressive Disorder (MDD) Bupropion hydrochloride extended-release tablets (XL) are indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The efficacy of the immediate-release formulation of bupropion was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult patients with MDD. The efficacy of the sustained-release formulation of bupropion in the maintena…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 077285

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 077285
ProductStrengthForm · routeLabelerProduct NDC
Bupropion HydrochlorideBupropion hydrochloride 300 mg/1Tablet, Extended releaseOralActavis Pharma, Inc.45963-142
Bupropion HydrochlorideBupropion hydrochloride 300 mg/1Tablet, Extended releaseOralAsclemed USA, Inc.76420-812
Bupropion HydrochlorideBupropion hydrochloride 300 mg/1Tablet, Extended releaseOralProficient Rx LP63187-819

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