Bupropion Hydrochloride NDC 45963-142

NDC codes

FDA NDC Directory

Product NDC (as listed)45963-142Labeler and product segments. Claims need a package NDC.

Product NDC at billing width45963-0142Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
45963-142-05	45963014205	500 TABLET, EXTENDED RELEASE in 1 BOTTLE (45963-142-05)Marketed from May 19, 2015
45963-142-30	45963014230	30 TABLET, EXTENDED RELEASE in 1 BOTTLE (45963-142-30)Marketed from Feb 17, 2015
45963-142-90	45963014290	90 TABLET, EXTENDED RELEASE in 1 BOTTLE (45963-142-90)Marketed from Jun 15, 2015

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Bupropion Hydrochloride
Generic name (nonproprietary): bupropion hydrochloride
Active ingredients: Bupropion hydrochloride — 300 mg/1
Dosage form: Tablet, Extended release
Route: Oral
Labeler: Actavis Pharma, Inc.
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 077285
Marketing start: Feb 17, 2015
Listing expires: Dec 31, 2027
Other FDA classes: Dopamine Uptake Inhibitors (Mechanism)Increased Dopamine Activity (Physiologic effect)Increased Norepinephrine Activity (Physiologic effect)Norepinephrine Uptake Inhibitors (Mechanism)
Identifiers: Product ID 45963-142_4792385c-d346-4e09-be99-3bde69490586SPL ID 4792385c-d346-4e09-be99-3bde69490586SPL set ID df923448-4f81-47af-8e55-f7359746b05fRxCUI 993557UNII ZG7E5POY8OUPC 0345963142306
Pharmacologic class: Aminoketone

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N445963014205 followed by a unit qualifier and the quantity

Package 45963-0142-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jul 9, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

Bupropion hydrochloride extended-release tablets (XL) are an aminoketone antidepressant, indicated for: treatment of major depressive disorder (MDD) ( 1.1 ) prevention of seasonal affective disorder (SAD) ( 1.2 ) 1.1 Major Depressive Disorder (MDD) Bupropion hydrochloride extended-release tablets (XL) are indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). The efficacy of the immediate-release formulation of bupropion was established in two 4-week controlled inpatient trials and one 6-week controlled outpatient trial of adult patients with MDD. The efficacy of the sustained-release formulation of bupropion in the maintena…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 077285

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 077285
Product	Strength	Form · route	Labeler	Product NDC
Bupropion Hydrochloride	Bupropion hydrochloride 300 mg/1	Tablet, Extended releaseOral	HAWAII REPACK, INC.	85534-0006
Bupropion Hydrochloride	Bupropion hydrochloride 300 mg/1	Tablet, Extended releaseOral	Asclemed USA, Inc.	76420-812
Bupropion Hydrochloride	Bupropion hydrochloride 300 mg/1	Tablet, Extended releaseOral	Proficient Rx LP	63187-819