NDC codes

FDA NDC Directory
Product NDC (as listed)72288-988Labeler and product segments. Claims need a package NDC.
Product NDC at billing width72288-0988Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
72288-988-75722880988751 BOTTLE in 1 CARTON (72288-988-75) / 90 TABLET, FILM COATED in 1 BOTTLE (72288-988-00)Marketed from Sep 3, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
naproxen sodium
Generic name (nonproprietary)
naproxen sodium
Active ingredients
Naproxen sodium — 220 mg/1
Dosage form
Tablet, Film coated
Route
Oral
Labeler
Amazon.com Services LLCNDC labeler code 72288
Product type
Over-the-counter drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 074661
Marketing start
Listing expires
Other FDA classes
Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)
Identifiers
Product ID 72288-988_cb2a3e4a-b62e-44fb-a286-d49c45ff60b6SPL ID cb2a3e4a-b62e-44fb-a286-d49c45ff60b6

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472288098875 followed by a unit qualifier and the quantity

Package 72288-0988-75. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 72288-988

What is NDC 72288-988?
72288-988 is the product NDC for naproxen sodium, Naproxen sodium 220 mg/1 tablet, film coated, listed with the FDA by Amazon.com Services LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
naproxen sodium.
What is the active ingredient?
Naproxen sodium.
Who is the labeler?
Amazon.com Services LLC, NDC labeler code 72288. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for naproxen sodium?
143 other product NDCs are listed under this name. See all naproxen sodium NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other naproxen sodium NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
Naproxen SodiumNaproxen sodium 550 mg/1TabletOralAdvanced Rx of Tennessee, LLC80425-057480425-0574-0180425-0574-0280425-0574-03
Naproxen SodiumNaproxen sodium 220 mg/1Tablet, CoatedOralHYVEE INC42507-24542507-0245-0142507-0245-14
Naproxen SodiumNaproxen sodium 220 mg/1Tablet, CoatedOralHYVEE INC42507-84442507-0844-0142507-0844-14
Naproxen SodiumNaproxen sodium 220 mg/1Capsule, Liquid filledOralTARGET Corporation11673-65111673-0651-78
Naproxen SodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralSafeway21130-59321130-0593-79
Naproxen SodiumNaproxen sodium 550 mg/1TabletOralAdvanced Rx of Tennessee, LLC80425-053180425-0531-0180425-0531-0280425-0531-03
Naproxen SodiumNaproxen sodium 550 mg/1TabletOralAdvanced Rx of Tennessee, LLC80425-053280425-0532-0180425-0532-0280425-0532-03
Naproxen SodiumNaproxen sodium 220 mg/1Tablet, CoatedOralCHAIN DRUG MARKETING ASSOCIATION, INC.83324-10883324-0108-0183324-0108-2483324-0108-50
Naproxen SodiumNaproxen sodium 220 mg/1Tablet, CoatedOralCHAIN DRUG MARKETING ASSOCIATION, INC.83324-10983324-0109-0183324-0109-50
Naproxen Sodiumnaproxen sodium 220mgNaproxen sodium 220 mg/1TabletOralCVS Pharmacy, Inc.51316-60851316-0608-90

All 144 naproxen sodium NDCs

Other NDCs under ANDA 074661

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 074661
ProductStrengthForm · routeLabelerProduct NDC
All Day Pain Reliefnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralWalgreen Company0363-0368
all day pain reliefnaproxen sodiumNaproxen sodium 200 mg/1Tablet, Film coatedOralWalgreen Company0363-0938
All Day Reliefnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralPublix Super Markets Inc56062-368
all day reliefnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralPublix Super Markets Inc56062-490
Basic Care Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralAmazon.com Services LLC72288-331
basic care naproxen sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralAmazon.com Services LLC72288-368
Basic Care Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralAmazon.com Services LLC72288-489
Berkley and Jensen Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralBJWC68391-368
betr headache pain reliefnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralLive Betr LLC80267-001
Care One Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralAmerican Sales Company41520-349
Care One Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralAmerican Sales Company41520-533
CareOne Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralAmerican Sales Company41520-507
DG Health Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralDolgencorp Inc55910-481
DG Health Naproxen Sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralDolgencorp Inc55910-490
dg health naproxen sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralDolgencorp Inc55910-500
dg health naproxen sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralDolgencorp Inc55910-729
equaline naproxen sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralUnited Natural Foods, Inc. dba UNFI41163-511
equaline naproxen sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralUnited Natural Foods, Inc. dba UNFI41163-707
exchange select naproxen sodiumnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralArmy & Air Force Exchange Service55301-368
foster and thrive all day pain reliefnaproxen sodiumNaproxen sodium 220 mg/1Tablet, Film coatedOralStrategic Sourcing Services LLC70677-1137

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