Twyneo NDC 51862-771

NDC codes

FDA NDC Directory

Product NDC (as listed)51862-771Labeler and product segments. Claims need a package NDC.

Product NDC at billing width51862-0771Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
51862-771-30	51862077130	1 BOTTLE, PUMP in 1 CARTON (51862-771-30) / 30 g in 1 BOTTLE, PUMPMarketed from Aug 1, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Twyneo
Generic name (nonproprietary): benzoyl peroxide and tretinoin
Active ingredients: Benzoyl peroxide — 30 mg/gTretinoin — 1 mg/g
Dosage form: Cream
Route: Topical
Labeler: Mayne Pharma Commercial LLC
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 214902
Marketing start: Aug 1, 2025
Listing expires: Dec 31, 2026
Other FDA classes: Retinoids (Chemical structure)
Identifiers: Product ID 51862-771_8557c350-45c9-48f8-8e1c-cc7569b3e7b6SPL ID 8557c350-45c9-48f8-8e1c-cc7569b3e7b6SPL set ID 654ae869-5bc0-40b3-a423-dcc3270c05d8RxCUI 2565807, 2565812UNII W9WZN9A0GM, 5688UTC01R
Pharmacologic class: Retinoid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N451862077130 followed by a unit qualifier and the quantity

Package 51862-0771-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Aug 11, 2025.

Indications (excerpt from the label)

TWYNEO is indicated for the topical treatment of acne vulgaris in adults and pediatric patients 9 years of age and older. TWYNEO is a combination tretinoin, a retinoid, and benzoyl peroxide indicated for the topical treatment of acne vulgaris in adults and pediatric patients 9 years of age and older. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 214902

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 214902
Product	Strength	Form · route	Labeler	Product NDC
Twyneotretinoin and benzoyl peroxide	Tretinoin 1 mg/g; Benzoyl peroxide 30 mg/g	CreamTopical	Galderma Laboratories, L.P.	0299-5945