NDC codes

FDA NDC Directory
Product NDC (as listed)0299-5945Labeler and product segments. Claims need a package NDC.
Product NDC at billing width00299-5945Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
0299-5945-00002995945006 g in 1 TUBE (0299-5945-00)Marketed from Mar 15, 2022 · Sample package
0299-5945-050029959450530 g in 1 BOTTLE, PUMP (0299-5945-05)Marketed from Jul 11, 2023 · Sample package
0299-5945-30002995945301 BOTTLE, PUMP in 1 BOX (0299-5945-30) / 30 g in 1 BOTTLE, PUMPMarketed from Mar 15, 2022

How the 11-digit form is made: The labeler segment has 4 digits, so one leading zero is added to it (4-4-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Twyneo
Generic name (nonproprietary)
tretinoin and benzoyl peroxide
Active ingredients
Tretinoin — 1 mg/gBenzoyl peroxide — 30 mg/g
Dosage form
Cream
Route
Topical
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 214902
Marketing start
Marketing end
Other FDA classes
Retinoids (Chemical structure)
Identifiers
Product ID 0299-5945_c8da4970-d262-4f55-a092-0a469789eb1fSPL ID c8da4970-d262-4f55-a092-0a469789eb1fSPL set ID 27208dff-e376-4c18-b56e-0a260f685a39RxCUI 2565807, 2565812UNII 5688UTC01R, W9WZN9A0GM
Pharmacologic class
Retinoid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N400299594500 followed by a unit qualifier and the quantity

Package 00299-5945-00. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

TWYNEO is indicated for the topical treatment of acne vulgaris in adults and pediatric patients 9 years of age and older. TWYNEO is a combination tretinoin, a retinoid, and benzoyl peroxide indicated for the topical treatment of acne vulgaris in adults and pediatric patients 9 years of age and older. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 214902

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 214902
ProductStrengthForm · routeLabelerProduct NDC
Twyneobenzoyl peroxide and tretinoinBenzoyl peroxide 30 mg/g; Tretinoin 1 mg/gCreamTopicalMayne Pharma Commercial LLC51862-771

Free account

Keep searching with a free account

You’ve used your 3 free searches for this session. Log in or create a free Med-Code account to keep looking up NDCs, J-codes and drugs.

Create a free accountLog in