Avopef (etoposide) NDC 83831-145

NDC codes

FDA NDC Directory

Product NDC (as listed)83831-145Labeler and product segments. Claims need a package NDC.

Product NDC at billing width83831-0145Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
83831-145-25	83831014525	1 VIAL in 1 CARTON (83831-145-25) / 25 mL in 1 VIALMarketed from Sep 14, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Avopef
Generic name (nonproprietary): etoposide
Active ingredients: Etoposide — 500 mg/25mL
Dosage form: Injection
Route: Intravenous
Labeler: AVYXA Pharma, LLC
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 220200
Marketing start: Sep 14, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Topoisomerase Inhibitors (Mechanism)
Identifiers: Product ID 83831-145_3421b13e-3145-4ca9-9fdb-2c1ff2b14e51SPL ID 3421b13e-3145-4ca9-9fdb-2c1ff2b14e51
Pharmacologic class: Topoisomerase Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N483831014525 followed by a unit qualifier and the quantity

Package 83831-0145-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

Other NDCs under NDA 220200

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 220200
Product	Strength	Form · route	Labeler	Product NDC
Avopefetoposide	Etoposide 100 mg/5mL	InjectionIntravenous	AVYXA Pharma, LLC	83831-144