What is NDC 81964-220?

81964-220 is the product NDC for Amoxicillin and Clavulanate Potassium, Amoxicillin 562.5 mg/1 + 2 more ingredients tablet, film coated, extended release, listed with the FDA by USAntibiotics, LLC. It has 2 package NDCs, shown above in 10- and 11-digit form.

What is the active ingredient?

Amoxicillin, Clavulanate potassium, Amoxicillin sodium.

USAntibiotics, LLC, NDC labeler code 81964. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Amoxicillin and Clavulanate Potassium?

200 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Amoxicillin and Clavulanate Potassium NDC 81964-220

NDC codes

FDA NDC Directory

Product NDC (as listed)81964-220Labeler and product segments. Claims need a package NDC.

Product NDC at billing width81964-0220Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
81964-220-28	8196402202881964022028	28 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (81964-220-28)Marketed from Dec 15, 2025
81964-220-40	8196402204081964022040	40 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (81964-220-40)Marketed from Dec 15, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Amoxicillin and Clavulanate Potassium
Generic name (nonproprietary): amoxicillin and clavulanate potassium
Active ingredients: Amoxicillin — 562.5 mg/1Clavulanate potassium — 62.5 mg/1Amoxicillin sodium — 437.5 mg/1
Dosage form: Tablet, Film coated, Extended release
Route: Oral
Labeler: USAntibiotics, LLCNDC labeler code 81964
Product type: Prescription drug
Marketing category: NDA authorized genericApplication NDA 050785
Marketing start: Dec 15, 2025
Listing expires: Dec 31, 2027
Other FDA classes: Penicillins (Chemical structure)Penicillins (Chemical structure)beta Lactamase Inhibitors (Mechanism)
Identifiers: Product ID 81964-220_52498ef2-86fc-72b6-e063-6294a90a4232SPL ID 52498ef2-86fc-72b6-e063-6294a90a4232SPL set ID 45c60b69-1b65-01ed-e063-6294a90a57beRxCUI 617995UNII 804826J2HU, Q42OMW3AT8, 544Y3D6MYHUPC 0381964220285, 0381964220407
Pharmacologic class: Penicillin-class Antibacterial; beta Lactamase Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N481964022028 followed by a unit qualifier and the quantity

Package 81964-0220-28. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jul 7, 2026.

Indications (excerpt from the label)

Amoxicillin and Clavulanate Potassium Extended Release Tablets is indicated for the treatment of infections in adults and pediatric patients weighing greater than or equal to 40 kg who are able to swallow tablets with: community-acquired pneumonia or acute bacterial sinusitis due to confirmed, or suspected beta-lactamase-producing pathogens (i.e., H. influenzae , M. catarrhalis , H. parainfluenzae , K. pneumoniae , or methicillin-susceptible S. aureus ) and S. pneumoniae with reduced susceptibility to penicillin (i.e., penicillin MICs equal to 2 mcg/mL). Limitations of Use Amoxicillin and Clavulanate Potassium Extended Release Tablets is not indicated for the treatment of infections due to S…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 81964-220

What is NDC 81964-220?: 81964-220 is the product NDC for Amoxicillin and Clavulanate Potassium, Amoxicillin 562.5 mg/1 + 2 more ingredients tablet, film coated, extended release, listed with the FDA by USAntibiotics, LLC. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Amoxicillin and Clavulanate Potassium.
What is the active ingredient?: Amoxicillin, Clavulanate potassium, Amoxicillin sodium.
Who is the labeler?: USAntibiotics, LLC, NDC labeler code 81964. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Amoxicillin and Clavulanate Potassium?: 200 other product NDCs are listed under this name. See all Amoxicillin and Clavulanate Potassium NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Amoxicillin and Clavulanate Potassium NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Amoxicillin And Clavulanate Potassium	Amoxicillin 875 mg/1; Clavulanate potassium 125 mg/1	Tablet, CoatedOral	REMEDYREPACK INC.	70518-4758	70518-4758-00
Amoxicillin and Clavulanate Potassium	Amoxicillin 400 mg/5mL; Clavulanic acid 57 mg/5mL	Powder, For suspensionOral	Preferred Pharmaceuticals Inc.	68788-4179	68788-4179-01
Amoxicillin And Clavulanate Potassium	Amoxicillin 500 mg/1; Clavulanate potassium 125 mg/1	Tablet, Film coatedOral	Coupler LLC	67046-0366	67046-0366-03
Amoxicillin and Clavulanate Potassium	Amoxicillin 875 mg/1; Clavulanate potassium 125 mg/1	Tablet, Film coatedOral	Coupler LLC	67046-0955	67046-0955-03
Amoxicillin and Clavulanate Potassium	Amoxicillin 875 mg/1; Clavulanate potassium 125 mg/1	Tablet, Film coatedOral	REMEDYREPACK INC.	70518-4424	70518-4424-00
Amoxicillin and Clavulanate Potassium	Amoxicillin 875 mg/1; Clavulanate potassium 125 mg/1	Tablet, Film coatedOral	Preferred Pharmaceuticals Inc.	68788-8836	68788-8836-02
Amoxicillin and Clavulanate Potassium	Amoxicillin 600 mg/5mL; Clavulanate potassium 42.9 mg/5mL	SuspensionOral	Preferred Pharmaceuticals Inc.	68788-8770	68788-8770-0168788-8770-07
Amoxicillin and Clavulanate Potassium	Amoxicillin 875 mg/1; Clavulanate potassium 125 mg/1	Tablet, Film coatedOral	Devatis, Inc.	73043-006	73043-0006-20
Amoxicillin and Clavulanate Potassium	Amoxicillin 500 mg/1; Clavulanate potassium 125 mg/1	Tablet, Film coatedOral	Devatis, Inc.	73043-007	73043-0007-20
Amoxicillin and Clavulanate Potassium	Amoxicillin 600 mg/5mL; Clavulanate potassium 42.9 mg/5mL	Powder, For suspensionOral	Devatis Inc.	73043-008	73043-0008-0173043-0008-0273043-0008-03

All 201 Amoxicillin and Clavulanate Potassium NDCs