NDC codes

FDA NDC Directory
Product NDC (as listed)81665-203Labeler and product segments. Claims need a package NDC.
Product NDC at billing width81665-0203Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
81665-203-01816650203011 VIAL, SINGLE-DOSE in 1 CARTON (81665-203-01) / 50 mL in 1 VIAL, SINGLE-DOSEMarketed from Feb 25, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
SODIUM PHENYLACETATE and SODIUM BENZOATE
Generic name (nonproprietary)
sodium phenylacetate and sodium benzoate
Active ingredients
Sodium phenylacetate — 100 mg/mLSodium benzoate — 100 mg/mL
Dosage form
Injection, Solution, Concentrate
Route
Intravenous
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 207096
Marketing start
Listing expires
Other FDA classes
Ammonium Ion Binding Activity (Mechanism)Ammonium Ion Binding Activity (Mechanism)
Identifiers
Product ID 81665-203_ab598188-342a-419e-9471-a7b60a25b198SPL ID ab598188-342a-419e-9471-a7b60a25b198SPL set ID 9067c301-74f9-457a-9b0f-b7e9b06a3508RxCUI 984118UNII 48N6U1781G, OJ245FE5EU
Pharmacologic class
Nitrogen Binding Agent

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N481665020301 followed by a unit qualifier and the quantity

Package 81665-0203-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Sodium Phenylacetate and Sodium Benzoate Injection, 10%/10% is indicated as adjunctive therapy in pediatric and adult patients for the treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle. During acute hyperammonemic episodes, arginine supplementation, caloric supplementation, dietary protein restriction, hemodialysis, and other ammonia lowering therapies should be considered [see Warnings and Precautions (5) ]. Sodium Phenylacetate and Sodium Benzoate Injection, 10%/10% is a nitrogen binding agent indicated as adjunctive therapy for the treatment of acute hyperammonemia and associated encephalopathy in patients with defic…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 207096

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 207096
ProductStrengthForm · routeLabelerProduct NDC
SODIUM PHENYLACETATE and SODIUM BENZOATESodium phenylacetate 100 mg/mL; Sodium benzoate 100 mg/mLInjection, Solution, ConcentrateIntravenousOmnivium Pharmaceuticals LLC81665-204
SODIUM PHENYLACETATE and SODIUM BENZOATESodium phenylacetate 100 mg/mL; Sodium benzoate 100 mg/mLInjection, Solution, ConcentrateIntravenousAilex Pharmaceuticals, LLC70556-100

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