NDC codes

FDA NDC Directory
Product NDC (as listed)81284-831Labeler and product segments. Claims need a package NDC.
Product NDC at billing width81284-0831Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
81284-831-05812840831055 AMPULE in 1 CARTON (81284-831-05) / 5 mL in 1 AMPULEMarketed from Oct 5, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Anticholium
Generic name (nonproprietary)
physostigmine salicylate
Active ingredients
Physostigmine salicylate — .4 mg/mL
Dosage form
Injection
Route
Intravenous
Product type
Prescription drug
Marketing category
Unapproved drug for use in drug shortage
Marketing start
Listing expires
Identifiers
Product ID 81284-831_7c1db393-3664-425f-af20-8d2175fb634eSPL ID 7c1db393-3664-425f-af20-8d2175fb634eSPL set ID b90b50e8-c8f1-4f2d-be6e-4d269b8c362cRxCUI 2666367, 2666374UNII 2046ZRO9VU

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N481284083105 followed by a unit qualifier and the quantity

Package 81284-0831-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Indications: ANTICHOLIUM ® is indicated for: 1. the use as an antidote and/or antagonist in case of intoxication with and/or overdose of: alcohol tropane alkaloids (hyoscyamine, atropine, scopolamine, as e.g. in brugmansia, datura, atropa belladonna) amanita pantherina and amanita muscaria tricyclic antidepressants (amitriptyline, imipramine, trimipramine, clomipramine, doxepine) antiemetics/antihistamines (phenothiazine, thioridazine, chlorpromazine, promethazine, diphenhydramine, dimenhydrinate) neuroleptic drugs (especially butyrophenones) benzodiazepines tolterodine, oxybutynine amantadine, diphenhydramine baclofen 4-hydroxybutyric acid (GHB) inhalation anesthetics ketamine 3-quinuclidin…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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