NDC codes

FDA NDC Directory
Product NDC (as listed)80425-0497Labeler and product segments. Claims need a package NDC.
Product NDC at billing width80425-0497Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
80425-0497-18042504970130 CAPSULE in 1 BOTTLE (80425-0497-1)Marketed from Feb 14, 2025

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Butalbital, Acetaminophen And Caffeine
Generic name (nonproprietary)
butalbital, acetaminophen and caffeine
Active ingredients
Butalbital — 50 mg/1Acetaminophen — 300 mg/1Caffeine — 40 mg/1
Dosage form
Capsule
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 214087
Marketing start
Listing expires
DEA schedule
CIII
Other FDA classes
Barbiturates (Chemical structure)Central Nervous System Stimulation (Physiologic effect)Xanthines (Chemical structure)
Identifiers
Product ID 80425-0497_2e20e0f9-ff3c-5d55-e063-6294a90a13ebSPL ID 2e20e0f9-ff3c-5d55-e063-6294a90a13ebSPL set ID 2e20e0ee-dd73-6287-e063-6294a90a03b1RxCUI 889520UNII KHS0AZ4JVK, 362O9ITL9D, 3G6A5W338E
Pharmacologic class
Barbiturate; Central Nervous System Stimulant; Methylxanthine

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N480425049701 followed by a unit qualifier and the quantity

Package 80425-0497-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Butalbital, acetaminophen and caffeine capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache. Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habit-forming and potentially abusable.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 214087

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 214087
ProductStrengthForm · routeLabelerProduct NDC
Butalbital, Acetaminophen And CaffeineButalbital 50 mg/1 + 2 more ingredientsCapsuleOralSeton Pharmaceuticals LLC13925-535
Butalbital, Acetaminophen And CaffeineButalbital 50 mg/1 + 2 more ingredientsCapsuleOralSeton Pharmaceuticals LLC13925-536
Butalbital, Acetaminophen And CaffeineButalbital 50 mg/1 + 2 more ingredientsCapsuleOralSOLCO HEALTHCARE US, LLC43547-686
Butalbital, Acetaminophen And CaffeineButalbital 50 mg/1 + 2 more ingredientsCapsuleOralAmici Pharma, Inc.69292-305

Free account

Keep searching with a free account

You’ve used your 3 free searches for this session. Log in or create a free Med-Code account to keep looking up NDCs, J-codes and drugs.

Create a free accountLog in