Loperamide Hydrochloride NDC 72888-130

NDC codes

FDA NDC Directory

Product NDC (as listed)72888-130Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72888-0130Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
72888-130-00	72888013000	1000 CAPSULE in 1 BOTTLE (72888-130-00)Marketed from Jan 26, 2023
72888-130-01	72888013001	100 CAPSULE in 1 BOTTLE (72888-130-01)Marketed from Jan 26, 2023
72888-130-05	72888013005	500 CAPSULE in 1 BOTTLE (72888-130-05)Marketed from Jan 26, 2023
72888-130-30	72888013030	30 CAPSULE in 1 BOTTLE (72888-130-30)Marketed from Jan 26, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Loperamide Hydrochloride
Generic name (nonproprietary): loperamide hydrochloride
Active ingredients: Loperamide hydrochloride — 2 mg/1
Dosage form: Capsule
Route: Oral
Labeler: Advagen Pharma Ltd.,
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 216876
Marketing start: Jan 26, 2023
Listing expires: Dec 31, 2027
Other FDA classes: Opioid Agonists (Mechanism)
Identifiers: Product ID 72888-130_47a17dfd-6255-f6f5-e063-6294a90a5660SPL ID 47a17dfd-6255-f6f5-e063-6294a90a5660SPL set ID 03c907d5-87f8-47a6-9544-5a24f5272739RxCUI 978006UNII 77TI35393CUPC 0372888130019, 0372888130057, 0372888130309, 0372888130002
Pharmacologic class: Opioid Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472888013000 followed by a unit qualifier and the quantity

Package 72888-0130-00. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 5, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Loperamide hydrochloride capsules are indicated for the control and symptomatic relief of acute nonspecific diarrhea in patients 2 years of age and older and of chronic diarrhea in adults associated with inflammatory bowel disease. Loperamide hydrochloride capsules are also indicated for reducing the volume of discharge from ileostomies.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 216876

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 216876
Product	Strength	Form · route	Labeler	Product NDC
Loperamide Hydrochloride	Loperamide hydrochloride 2 mg/1	CapsuleOral	Bryant Ranch Prepack	71335-2487
Loperamide Hydrochloride	Loperamide hydrochloride 2 mg/1	CapsuleOral	NCS HealthCare of KY, LLC dba Vangard Labs	0615-8497