NDC codes

FDA NDC Directory
Product NDC (as listed)72865-310Labeler and product segments. Claims need a package NDC.
Product NDC at billing width72865-0310Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
72865-310-10728650310101000 TABLET in 1 BOTTLE (72865-310-10)Marketed from Apr 1, 2026
72865-310-1872865031018180 TABLET in 1 BOTTLE (72865-310-18)Marketed from Sep 30, 2025
72865-310-607286503106060 TABLET in 1 BOTTLE (72865-310-60)Marketed from Sep 30, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Sacubitril and Valsartan
Generic name (nonproprietary)
sacubitril and valsartan
Active ingredients
Sacubitril — 24 mg/1Valsartan — 26 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 213728
Marketing start
Listing expires
Other FDA classes
Angiotensin 2 Receptor Antagonists (Mechanism)Neprilysin Inhibitors (Mechanism)
Identifiers
Product ID 72865-310_c4dddf41-2e19-4fd1-8f2a-6b33a804ed40SPL ID c4dddf41-2e19-4fd1-8f2a-6b33a804ed40SPL set ID 064a7c51-de30-4759-8210-e18438e6a187RxCUI 1656340, 1656349, 1656354UNII 80M03YXJ7I, 17ERJ0MKGIUPC 0372865312100, 0372865311189, 0372865310601, 0372865312186, 0372865311103, 0372865311608, 0372865310106, 0372865312605, 0372865310182
Pharmacologic class
Angiotensin 2 Receptor Blocker; Neprilysin Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472865031010 followed by a unit qualifier and the quantity

Package 72865-0310-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

Sacubitril and valsartan tablets are a combination of sacubitril, a neprilisin inhibitor, and valsartan, an angiotensin II receptor blocker, and sacubitril and valsartan tablets are indicated: • to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. Benefits are most clearly evident in patients with left ventricular ejection fraction (LVEF) below normal. ( 1.1 ) • for the treatment of symptomatic heart failure with systemic left ventricular systolic dysfunction in pediatric patients aged one year and older. Sacubitril and valsartan reduces NT-proBNP and is expected to improve cardiovascular outcomes. ( 1.2 ) 1.1 Adult He…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 213728

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 213728
ProductStrengthForm · routeLabelerProduct NDC
Sacubitril and ValsartanSacubitril 24 mg/1; Valsartan 26 mg/1TabletOralMacleods Pharmaceuticals Limited33342-570
Sacubitril and ValsartanSacubitril 49 mg/1; Valsartan 51 mg/1TabletOralMacleods Pharmaceuticals Limited33342-571
Sacubitril and ValsartanSacubitril 97 mg/1; Valsartan 103 mg/1TabletOralMacleods Pharmaceuticals Limited33342-572
Sacubitril and ValsartanSacubitril 49 mg/1; Valsartan 51 mg/1TabletOralAphena Pharma Solutions - Tennessee, LLC71610-982
Sacubitril and ValsartanSacubitril 24 mg/1; Valsartan 26 mg/1TabletOralAphena Pharma Solutions - Tennessee, LLC71610-983
Sacubitril and ValsartanSacubitril 97 mg/1; Valsartan 103 mg/1TabletOralAphena Pharma Solutions - Tennessee, LLC71610-984
Sacubitril and ValsartanSacubitril 97 mg/1; Valsartan 103 mg/1Tablet, Film coatedOralNorthStar RxLLC72603-882
Sacubitril and ValsartanSacubitril 24 mg/1; Valsartan 26 mg/1Tablet, Film coatedOralNorthStar RxLLC72603-880
Sacubitril and ValsartanSacubitril 49 mg/1; Valsartan 51 mg/1Tablet, Film coatedOralNorthStar RxLLC72603-881
Sacubitril and ValsartanSacubitril 49 mg/1; Valsartan 51 mg/1TabletOralXLCare Pharmaceuticals Inc72865-311
Sacubitril and ValsartanSacubitril 97 mg/1; Valsartan 103 mg/1TabletOralXLCare Pharmaceuticals Inc72865-312

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