Estradiol NDC 72603-243

NDC codes

FDA NDC Directory

Product NDC (as listed)72603-243Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72603-0243Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72603-243-30	72603024330	30 PACKET in 1 CARTON (72603-243-30) / .75 g in 1 PACKET (72603-243-01)Marketed from Dec 18, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Estradiol
Generic name (nonproprietary): estradiol
Active ingredients: Estradiol — .75 mg/.75g
Dosage form: Gel
Route: Topical
Labeler: NorthStar Rx LLC
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 217610
Marketing start: Dec 18, 2023
Listing expires: Dec 31, 2026
Other FDA classes: Estradiol Congeners (Chemical structure)Estrogen Receptor Agonists (Mechanism)
Identifiers: Product ID 72603-243_37b3aa97-b1e5-fe8e-e063-6294a90a48c4SPL ID 37b3aa97-b1e5-fe8e-e063-6294a90a48c4SPL set ID 0c8a07a4-5762-eaf4-e063-6394a90a54ffRxCUI 2619677, 2619679, 2619681, 2619683, 2619685UNII 4TI98Z838E
Pharmacologic class: Estrogen

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472603024330 followed by a unit qualifier and the quantity

Package 72603-0243-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 16, 2025. This label includes a boxed warning.

Indications (excerpt from the label)

1.1 Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause Estradiol gel is an estrogen indicated for the treatment of moderate to severe vasomotor symptoms due to menopause (1.1).

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)