What is NDC 72189-625?

72189-625 is the product NDC for Hydrocortisone Cream, Hydrocortisone 25 mg/g cream, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.

Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Hydrocortisone Cream?

4 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Hydrocortisone Cream NDC 72189-625 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)72189-625Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72189-0625Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72189-625-30	72189062530	1 g in 1 TUBE (72189-625-30)Marketed from May 29, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Hydrocortisone Cream
Generic name (nonproprietary): hydrocortisone cream
Active ingredients: Hydrocortisone — 25 mg/g
Dosage form: Cream
Route: Topical
Labeler: Direct_RxNDC labeler code 72189
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 089414
Marketing start: May 29, 2025
Listing expires: Dec 31, 2027
Other FDA classes: Corticosteroid Hormone Receptor Agonists (Mechanism)
Identifiers: Product ID 72189-625_4d3aae17-8c40-dd5f-e063-6394a90af6edSPL ID 4d3aae17-8c40-dd5f-e063-6394a90af6edSPL set ID 364af43e-c1a9-3f03-e063-6294a90a14f5RxCUI 310891UNII WI4X0X7BPJ
Pharmacologic class: Corticosteroid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472189062530 followed by a unit qualifier and the quantity

Package 72189-0625-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 17, 2026.

Indications (excerpt from the label)

Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72189-625

What is NDC 72189-625?: 72189-625 is the product NDC for Hydrocortisone Cream, Hydrocortisone 25 mg/g cream, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Hydrocortisone Cream.
What is the active ingredient?: Hydrocortisone.
Who is the labeler?: Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Hydrocortisone Cream?: 4 other product NDCs are listed under this name. See all Hydrocortisone Cream NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Hydrocortisone Cream NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Hydrocortisone Cream	Hydrocortisone 25 mg/g	CreamTopical	Direct_Rx	72189-554	72189-0554-2872189-0554-30
Hydrocortisone Creamhydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Trifecta Pharmaceuticals USA	69396-147	69396-0147-01
Hydrocortisone Creamhydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Trifecta Pharmaceuticals USA	69396-096	69396-0096-16
Hydrocortisone Creamhydrocortisone	Hydrocortisone 1 g/100g	CreamTopical	Trifecta Pharmaceuticals USA	69396-028	69396-0028-0169396-0028-0269396-0028-33+1 more

Other NDCs under ANDA 089414

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 089414
Product	Strength	Form · route	Labeler	Product NDC
Hydrocortisone	Hydrocortisone 25 mg/g	CreamTopical	E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC	0168-0080
Hydrocortisone	Hydrocortisone 25 mg/g	CreamTopical	Sportpharm LLC	85766-081