What is NDC 72189-616?

72189-616 is the product NDC for Ciprofloxacin, Ciprofloxacin hydrochloride 250 mg/1 tablet, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.

Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Ciprofloxacin?

169 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Ciprofloxacin NDC 72189-616 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)72189-616Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72189-0616Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72189-616-06	72189061606	6 TABLET in 1 BOTTLE (72189-616-06)Marketed from Feb 25, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Ciprofloxacin
Generic name (nonproprietary): ciprofloxacin
Active ingredients: Ciprofloxacin hydrochloride — 250 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Direct_RxNDC labeler code 72189
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 208921
Marketing start: Feb 25, 2025
Listing expires: Dec 31, 2026
Other FDA classes: Cytochrome P450 1A2 Inhibitors (Mechanism)Fluoroquinolones (Chemical structure)
Identifiers: Product ID 72189-616_2efbda2a-fc98-b7c5-e063-6294a90a362dSPL ID 2efbda2a-fc98-b7c5-e063-6294a90a362dSPL set ID 2efbda2a-fc97-b7c5-e063-6294a90a362dRxCUI 197511UNII 4BA73M5E37
Pharmacologic class: Fluoroquinolone Antibacterial

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472189061606 followed by a unit qualifier and the quantity

Package 72189-0616-06. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Feb 25, 2025. This label includes a boxed warning.

Indications (excerpt from the label)

Click here to enter Indications 1.1 Skin and Skin Structure Infections Ciprofloxacin tablets are indicated in adult patients for treatment of skin and skin structure infections caused by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Morganella morganii, Citrobacter freundii, Pseudomonas aeruginosa, methicillin-susceptible Staphylococcus aureus, methicillin-susceptible Staphylococcus epidermidis, or Streptococcus pyogenes. 1.2 Bone and Joint Infections Ciprofloxacin tablets are indicated in adult patients for treatment of bone and joint infections caused by Enterobacter cloacae, Serratia marcescens, or Pseudomonas aer…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72189-616

What is NDC 72189-616?: 72189-616 is the product NDC for Ciprofloxacin, Ciprofloxacin hydrochloride 250 mg/1 tablet, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Ciprofloxacin.
What is the active ingredient?: Ciprofloxacin hydrochloride.
Who is the labeler?: Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Ciprofloxacin?: 169 other product NDCs are listed under this name. See all Ciprofloxacin NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Ciprofloxacin NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Ciprofloxacinciprofloxacin hydrochloride	Ciprofloxacin hydrochloride 500 mg/1	Tablet, Film coatedOral	American Health Packaging	60687-947	60687-0947-01
ciprofloxacin	Ciprofloxacin hydrochloride 250 mg/1	Tablet, Film coatedOral	Northwind Health Company, LLC	82868-102	82868-0102-1482868-0102-20
ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	Tablet, Film coatedOral	Cardinal Health 107, LLC	55154-0193	55154-0193-00
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	Tablet, Film coatedOral	Direct_Rx	72189-627	72189-0627-1072189-0627-14
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	Preferred Pharmaceuticals Inc.	68788-8875	68788-8875-0068788-8875-0168788-8875-02+4 more
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	Direct_Rx	72189-623	72189-0623-1072189-0623-1472189-0623-20
Ciprofloxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	St. Mary's Medical Park Pharmacy	60760-690	60760-0690-10
Ciprofloxacinciprofloxacin hydrochloride	Ciprofloxacin hydrochloride 500 mg/1	Tablet, Film coatedOral	NCS HealthCare of KY, LLC dba Vangard Labs	0615-8630	00615-8630-1000615-8630-1400615-8630-20
Ciprofloxacinciprofloxacin hydrochloride	Ciprofloxacin hydrochloride 500 mg/1	Tablet, Film coatedOral	Aurobindo Pharma Limited	59651-977	59651-0977-0159651-0977-0559651-0977-20+2 more
Ciprofloxacinciprofloxacin hydrochloride	Ciprofloxacin hydrochloride 250 mg/1	Tablet, Film coatedOral	Aurobindo Pharma Limited	59651-976	59651-0976-0159651-0976-2059651-0976-30+1 more

All 170 Ciprofloxacin NDCs

Other NDCs under ANDA 208921

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 208921
Product	Strength	Form · route	Labeler	Product NDC
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	Tablet, CoatedOral	Redpharm Drug	67296-1848
Ciprofloxacin	Ciprofloxacin hydrochloride 250 mg/1	Tablet, CoatedOral	Direct Rx	72189-323
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	A-S Medication Solutions	50090-7297
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0492
Ciprofloxacinciprofloxacin tablets	Ciprofloxacin hydrochloride 500 mg/1	Tablet, CoatedOral	Yiling Pharmaceutical, Inc.	69117-0009
Ciprofloxacinciprofloxacin tablets	Ciprofloxacin hydrochloride 250 mg/1	Tablet, CoatedOral	Yiling Pharmaceutical, Inc.	69117-0008
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	Direct_Rx	72189-623
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	Coupler LLC	67046-1460
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	Bryant Ranch Prepack	72162-2425
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	Tablet, CoatedOral	Bryant Ranch Prepack	71335-2054
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	REMEDYREPACK INC.	70518-4229
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	NuCare Pharmaceuticals,Inc.	68071-3610
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	Tablet, CoatedOral	Northwind Health Company, LLC	51655-490
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	PD-Rx Pharmaceuticals, Inc.	72789-519
Ciprofloxacin	Ciprofloxacin hydrochloride 500 mg/1	Tablet, CoatedOral	St. Mary's Medical Park Pharmacy	60760-676
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	Redpharm Drug	67296-2135
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 500 mg/1	TabletOral	ST. MARY'S MEDICAL PARK PHARMACY	60760-689
Ciprofloxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	St. Mary's Medical Park Pharmacy	60760-690
Ciprofloxacin	Ciprofloxacin hydrochloride 250 mg/1	Tablet, CoatedOral	Bryant Ranch Prepack	71335-2097
Ciprofloxacinciprofolxacin	Ciprofloxacin hydrochloride 250 mg/1	TabletOral	NuCare Pharmaceuticals,Inc.	68071-3901

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