NDC codes

FDA NDC Directory
Product NDC (as listed)71872-7331Labeler and product segments. Claims need a package NDC.
Product NDC at billing width71872-7331Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
71872-7331-1718727331011 VIAL, MULTI-DOSE in 1 BAG (71872-7331-1) / 10 mL in 1 VIAL, MULTI-DOSEMarketed from Nov 15, 2024

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Nalbuphine hydrochloride
Generic name (nonproprietary)
nalbuphine hydrochloride
Active ingredients
Nalbuphine hydrochloride — 10 mg/mL
Dosage form
Injection
Route
Intramuscular, Intravenous, Subcutaneous
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 216049
Marketing start
Listing expires
Other FDA classes
Competitive Opioid Antagonists (Mechanism)Partial Opioid Agonists (Mechanism)
Identifiers
Product ID 71872-7331_292b0d0e-f223-d384-e063-6394a90acd44SPL ID 292b0d0e-f223-d384-e063-6394a90acd44SPL set ID 292b0d0e-f222-d384-e063-6394a90acd44RxCUI 904415UNII ZU4275277RUPC 0370069661017
Pharmacologic class
Opioid Agonist/Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N471872733101 followed by a unit qualifier and the quantity

Package 71872-7331-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Nalbuphine hydrochloride injection is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Nalbuphine hydrochloride injection can also be used as a supplement to balanced anesthesia, for preoperative and postoperative analgesia, and for obstetrical analgesia during labor and delivery. Limitations of Use: Because of the risks of addiction, abuse, and misuse, with opioids, which can occur at any dosage or duration [see WARNINGS ], reserve nalbuphine hydrochloride injection for use in patients for whom alternative treatment options [e.g., non-opioid analgesics]: Have not been tolerated, or ar…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 216049

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 216049
ProductStrengthForm · routeLabelerProduct NDC
Nalbuphine HydrochlorideNalbuphine hydrochloride 20 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousHenry Schein, Inc.0404-9766
Nalbuphine HydrochlorideNalbuphine hydrochloride 10 mg/mLInjectionIntramuscular, Intravenous, SubconjunctivalHenry Schein, Inc.0404-9767
Nalbuphine hydrochlorideNalbuphine hydrochloride 20 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousSomerset Therapeutics, LLC70069-662
Nalbuphine hydrochlorideNalbuphine hydrochloride 10 mg/mLInjectionIntramuscular, Intravenous, SubcutaneousSomerset Therapeutics, LLC70069-661

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