What is NDC 70727-497?

70727-497 is the product NDC for Rhopressa (netarsudil), Netarsudil mesylate .2 mg/mL solution/ drops, listed with the FDA by Alcon Laboratories, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

Alcon Laboratories, Inc., NDC labeler code 70727. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Rhopressa?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Rhopressa NDC 70727-497 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)70727-497Labeler and product segments. Claims need a package NDC.

Product NDC at billing width70727-0497Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
70727-497-25	70727049725	1 BOTTLE in 1 CARTON (70727-497-25) / 2.5 mL in 1 BOTTLEMarketed from Dec 18, 2017
70727-497-99	70727049799	1 BOTTLE in 1 CARTON (70727-497-99) / 2.5 mL in 1 BOTTLEMarketed from Dec 18, 2017 · Sample package

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Rhopressa
Generic name (nonproprietary): netarsudil
Active ingredients: Netarsudil mesylate — .2 mg/mL
Dosage form: Solution/ drops
Route: Ophthalmic, Topical
Labeler: Alcon Laboratories, Inc.NDC labeler code 70727
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 208254
Marketing start: Dec 18, 2017
Listing expires: Dec 31, 2027
Other FDA classes: Rho Kinase Inhibitors (Mechanism)
Identifiers: Product ID 70727-497_82acde68-4935-4dc9-82ff-9ff7f449f893SPL ID 82acde68-4935-4dc9-82ff-9ff7f449f893SPL set ID 7d4f0e3a-5b86-4c43-982a-813b22ae7e22RxCUI 1992868, 1992873UNII VL756B1K0UUPC 0370727497255
Pharmacologic class: Rho Kinase Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Ophthalmic, Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N470727049725 followed by a unit qualifier and the quantity

Package 70727-0497-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 20, 2026.

Indications (excerpt from the label)

RHOPRESSA is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. RHOPRESSA ® is a Rho kinase inhibitor indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 70727-497

What is NDC 70727-497?: 70727-497 is the product NDC for Rhopressa (netarsudil), Netarsudil mesylate .2 mg/mL solution/ drops, listed with the FDA by Alcon Laboratories, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Rhopressa (Netarsudil).
What is the active ingredient?: Netarsudil mesylate.
Who is the labeler?: Alcon Laboratories, Inc., NDC labeler code 70727. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Rhopressa?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Rhopressa (Netarsudil) NDC 70727-497