NDC codes

FDA NDC Directory
Product NDC (as listed)68308-766Labeler and product segments. Claims need a package NDC.
Product NDC at billing width68308-0766Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
68308-766-30683080766301 TUBE in 1 CARTON (68308-766-30) / 30 g in 1 TUBEMarketed from Jul 15, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Rhofade
Generic name (nonproprietary)
oxymetazoline hydrochloride
Active ingredients
Oxymetazoline hydrochloride — 10 mg/g
Dosage form
Cream
Route
Topical
Labeler
Mayne PharmaNDC labeler code 68308
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 208552
Marketing start
Listing expires
Other FDA classes
Imidazolines (Chemical structure)Increased Sympathetic Activity (Physiologic effect)Vasoconstriction (Physiologic effect)
Identifiers
Product ID 68308-766_a49cde4c-e484-4cb9-85c2-35ba41690f35SPL ID a49cde4c-e484-4cb9-85c2-35ba41690f35SPL set ID 34298db6-647d-480d-88a8-dc53258a5164RxCUI 1869816, 1869821UNII K89MJ0S5VY
Pharmacologic class
Vasoconstrictor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N468308076630 followed by a unit qualifier and the quantity

Package 68308-0766-30. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Oxymetazoline Hydrochloride Cream, 1% is indicated for the topical treatment of persistent facial erythema associated with rosacea in adults. Oxymetazoline Hydrochloride Cream is an alpha 1A adrenoceptor agonist indicated for the topical treatment of persistent facial erythema associated with rosacea in adults. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 68308-766

What is NDC 68308-766?
68308-766 is the product NDC for Rhofade (oxymetazoline hydrochloride), Oxymetazoline hydrochloride 10 mg/g cream, listed with the FDA by Mayne Pharma. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Rhofade (Oxymetazoline hydrochloride).
What is the active ingredient?
Oxymetazoline hydrochloride.
Who is the labeler?
Mayne Pharma, NDC labeler code 68308. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Rhofade?
2 other product NDCs are listed under this name. See all Rhofade NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Rhofade NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
Rhofadeoxymetazoline hydrochlorideOxymetazoline hydrochloride 10 mg/gCreamTopicalMayne Pharma51862-76551862-0765-0051862-0765-30
Rhofadeoxymetazoline hydrochlorideOxymetazoline hydrochloride 1 g/100gCreamTopicalEPI Health, LLC71403-00371403-0003-1571403-0003-30

Other NDCs under NDA 208552

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 208552
ProductStrengthForm · routeLabelerProduct NDC
Rhofadeoxymetazoline hydrochlorideOxymetazoline hydrochloride 1 g/100gCreamTopicalEPI Health, LLC71403-003
Rhofadeoxymetazoline hydrochlorideOxymetazoline hydrochloride 10 mg/gCreamTopicalMayne Pharma51862-765

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