What is NDC 68083-668?

68083-668 is the product NDC for Leucovorin Calcium, Leucovorin calcium 500 mg/50mL injection, powder, lyophilized, for solution, listed with the FDA by Gland Pharma Limited. It has 1 package NDC, shown above in 10- and 11-digit form.

Gland Pharma Limited, NDC labeler code 68083. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Leucovorin Calcium?

54 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Leucovorin Calcium NDC 68083-668 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)68083-668Labeler and product segments. Claims need a package NDC.

Product NDC at billing width68083-0668Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
68083-668-01	6808306680168083066801	1 VIAL in 1 CARTON (68083-668-01) / 50 mL in 1 VIALMarketed from Oct 14, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Leucovorin Calcium
Generic name (nonproprietary): leucovorin calcium
Active ingredients: Leucovorin calcium — 500 mg/50mL
Dosage form: Injection, Powder, Lyophilized, For solution
Route: Intramuscular, Intravenous
Labeler: Gland Pharma LimitedNDC labeler code 68083
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 218200
Marketing start: Oct 14, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Folic Acid (Chemical structure)
Identifiers: Product ID 68083-668_782dbace-df38-43ca-b58b-ff1d89892167SPL ID 782dbace-df38-43ca-b58b-ff1d89892167SPL set ID 82c445f5-4cb7-4457-af19-3b5b8a121b4fRxCUI 2055036UNII RPR1R4C0P4UPC 0368083668013
Pharmacologic class: Folate Analog

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N468083066801 followed by a unit qualifier and the quantity

Package 68083-0668-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Oct 15, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE Leucovorin calcium rescue is indicated after high dose methotrexate therapy in osteosarcoma. Leucovorin calcium is also indicated to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists. Leucovorin calcium is indicated in the treatment of megaloblastic anemias due to folic acid deficiency when oral therapy is not feasible. Leucovorin is also indicated for use in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. Leucovorin should not be mixed in the same infusion as 5-fluorouracil because a precipitate may fo…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 68083-668

What is NDC 68083-668?: 68083-668 is the product NDC for Leucovorin Calcium, Leucovorin calcium 500 mg/50mL injection, powder, lyophilized, for solution, listed with the FDA by Gland Pharma Limited. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Leucovorin Calcium.
What is the active ingredient?: Leucovorin calcium.
Who is the labeler?: Gland Pharma Limited, NDC labeler code 68083. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Leucovorin Calcium?: 54 other product NDCs are listed under this name. See all Leucovorin Calcium NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Leucovorin Calcium NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Leucovorin Calcium	Leucovorin calcium 25 mg/1	TabletOral	Major Pharmaceuticals	0904-7584	00904-7584-10
Leucovorin Calcium	Leucovorin calcium 350 mg/17.5mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	Gland Pharma Limited	68083-587	68083-0587-01
Leucovorin Calcium	Leucovorin calcium 350 mg/17.5mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	GLENMARK PHARMACEUTICALS INC., USA	68462-767	68462-0767-35
leucovorin calcium	Leucovorin calcium 100 mg/10mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	BluePoint Laboratories	68001-648	68001-0648-36
leucovorin calcium	Leucovorin calcium 200 mg/20mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	BluePoint Laboratories	68001-649	68001-0649-37
leucovorin calcium	Leucovorin calcium 350 mg/17.5mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	BluePoint Laboratories	68001-650	68001-0650-38
Leucovorin Calcium	Leucovorin calcium 350 mg/1	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	Slate Run Pharmaceuticals, LLC	70436-119	70436-0119-80
leucovorin calcium	Leucovorin calcium 50 mg/5mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	Meitheal Pharmaceuticals Inc.	71288-160	71288-0160-10
leucovorin calcium	Leucovorin calcium 100 mg/10mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	Meitheal Pharmaceuticals Inc.	71288-161	71288-0161-20
leucovorin calcium	Leucovorin calcium 200 mg/20mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	Meitheal Pharmaceuticals Inc.	71288-162	71288-0162-30

All 55 Leucovorin Calcium NDCs

Other NDCs under ANDA 218200

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 218200
Product	Strength	Form · route	Labeler	Product NDC
Leucovorin Calcium	Leucovorin calcium 350 mg/17.5mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	Gland Pharma Limited	68083-587
Leucovorin Calcium	Leucovorin calcium 350 mg/17.5mL	Injection, Powder, Lyophilized, For solutionIntramuscular, Intravenous	GLENMARK PHARMACEUTICALS INC., USA	68462-767