Xylocaine NDC 66312-176

NDC codes

FDA NDC Directory

Product NDC (as listed)66312-176Labeler and product segments. Claims need a package NDC.

Product NDC at billing width66312-0176Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
66312-176-16	66312017616	50 CARTRIDGE in 1 CARTON (66312-176-16) / 1.7 mL in 1 CARTRIDGEMarketed from Apr 14, 2009

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Xylocaine
Generic name (nonproprietary): lidocaine hydrochloride and epinephrine bitartrate
Active ingredients: Lidocaine hydrochloride — 20 mg/mLEpinephrine bitartrate — 10 ug/mL
Dosage form: Injection, Solution
Route: Submucosal
Labeler: Dentsply Pharmaceutical
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 088390
Marketing start: Jan 22, 1985
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic alpha-Agonists (Mechanism)Adrenergic beta-Agonists (Mechanism)Amides (Chemical structure)Catecholamines (Chemical structure)Local Anesthesia (Physiologic effect)
Identifiers: Product ID 66312-176_d14d0eb3-a481-4c68-a0cd-75aae0622fd1SPL ID d14d0eb3-a481-4c68-a0cd-75aae0622fd1SPL set ID 14b55cf9-f7cd-4bb4-a7c5-aba61abadef1RxCUI 1010768, 1293648, 1608499, 1657026UNII 30Q7KI53AK, V13007Z41A
Pharmacologic class: Amide Local Anesthetic; Antiarrhythmic; Catecholamine; alpha-Adrenergic Agonist; beta-Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N466312017616 followed by a unit qualifier and the quantity

Package 66312-0176-16. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Aug 13, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE 2% Xylocaine DENTAL Solutions are indicated for the production of local anesthesia for dental procedures by nerve block or infiltration techniques. Only accepted procedures for these techniques as described in standard textbooks are recommended.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 088390

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 088390
Product	Strength	Form · route	Labeler	Product NDC
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Patterson Dental	50227-1030
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	The Atlanta Dental Supply Company DBA Advanced Dental Products	71347-210
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Benco Dental	66975-425
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Henry Schein Inc.	0404-6512
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Safco Dental Supply Co	67239-0240
Lidocainelidocaine hydrochloride and epinephrine	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Septodont, Inc.	0362-0898
Lignospan Standardlidocaine hydrochloride and epinephrine	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Septodont, Inc.	0362-1095
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Darby Dental Supply, LLC	66467-9730
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	Novocol Pharmaceutical of Canada, Inc.	51004-2105
Lidocainelidocaine hydrochloride and epinephrine bitartrate	Lidocaine hydrochloride 20 mg/mL; Epinephrine bitartrate .01 mg/mL	Injection, SolutionSubmucosal	NDC, Inc.	43128-105