NDC codes

FDA NDC Directory
Product NDC (as listed)65250-266Labeler and product segments. Claims need a package NDC.
Product NDC at billing width65250-0266Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
65250-266-04652500266044 VIAL in 1 CARTON (65250-266-04) / 20 mL in 1 VIAL (65250-266-20)Marketed from Sep 28, 2016
65250-266-096525002660910 VIAL in 1 CARTON (65250-266-09) / 20 mL in 1 VIAL (65250-266-20)Marketed from Mar 31, 2017

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Exparel
Generic name (nonproprietary)
bupivacaine
Active ingredients
Bupivacaine — 13.3 mg/mL
Dosage form
Injection, Suspension, Liposomal
Route
Infiltration
Labeler
Pacira Pharmaceuticals, Inc.NDC labeler code 65250
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 022496
Marketing start
Listing expires
Other FDA classes
Amides (Chemical structure)Local Anesthesia (Physiologic effect)
Identifiers
Product ID 65250-266_7dd52279-ea2e-4f8c-8e29-8172bc3ed882SPL ID 7dd52279-ea2e-4f8c-8e29-8172bc3ed882SPL set ID bb5a9e59-0f51-11df-8a39-0800200c9a66RxCUI 1191508, 1191513, 1745061, 1745062UNII Y8335394RO
Pharmacologic class
Amide Local Anesthetic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N465250026604 followed by a unit qualifier and the quantity

Package 65250-0266-04. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

EXPAREL is indicated to produce postsurgical: Local analgesia via infiltration in patients aged 6 years and older Regional analgesia via an interscalene brachial plexus nerve block in adults Regional analgesia via a sciatic nerve block in the popliteal fossa in adults Regional analgesia via an adductor canal block in adults EXPAREL contains bupivacaine, an amide local anesthetic, and is indicated to produce postsurgical: Local analgesia via infiltration in patients aged 6 years and older ( 1 ). Regional analgesia via an interscalene brachial plexus nerve block in adults ( 1 ). Regional analgesia via a sciatic nerve block in the popliteal fossa in adults ( 1 ). Regional analgesia via an adduc…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 65250-266

What is NDC 65250-266?
65250-266 is the product NDC for Exparel (bupivacaine), Bupivacaine 13.3 mg/mL injection, suspension, liposomal, listed with the FDA by Pacira Pharmaceuticals, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Exparel (Bupivacaine).
What is the active ingredient?
Bupivacaine.
Who is the labeler?
Pacira Pharmaceuticals, Inc., NDC labeler code 65250. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Exparel?
1 other product NDC are listed under this name. See all Exparel NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Exparel NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
ExparelbupivacaineBupivacaine 13.3 mg/mLInjection, Suspension, LiposomalInfiltrationPacira Pharmaceuticals, Inc.65250-13365250-0133-0465250-0133-09

Other NDCs under NDA 022496

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 022496
ProductStrengthForm · routeLabelerProduct NDC
ExparelbupivacaineBupivacaine 13.3 mg/mLInjection, Suspension, LiposomalInfiltrationPacira Pharmaceuticals, Inc.65250-133

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