NDC codes

FDA NDC Directory
Product NDC (as listed)64850-643Labeler and product segments. Claims need a package NDC.
Product NDC at billing width64850-0643Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
64850-643-0164850064301100 TABLET in 1 BOTTLE (64850-643-01)Marketed from May 3, 2024
64850-643-0564850064305500 TABLET in 1 BOTTLE (64850-643-05)Marketed from Feb 10, 2025
64850-643-1264850064312120 TABLET in 1 BOTTLE (64850-643-12)Marketed from Sep 10, 2019

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Acetaminophen and Codeine Phosphate
Generic name (nonproprietary)
acetaminophen and codeine phosphate
Active ingredients
Acetaminophen — 300 mg/1Codeine phosphate — 60 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 212418
Marketing start
Listing expires
DEA schedule
CIII
Other FDA classes
Full Opioid Agonists (Mechanism)
Identifiers
Product ID 64850-643_d61159a3-cb34-4931-8185-e1eb41654a8aSPL ID d61159a3-cb34-4931-8185-e1eb41654a8aSPL set ID 6286e128-1288-4dc0-b14b-f04a0e2a22f9RxCUI 993770, 993781, 993890UNII GSL05Y1MN6, 362O9ITL9D
Pharmacologic class
Opioid Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N464850064301 followed by a unit qualifier and the quantity

Package 64850-0643-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Acetaminophen and codeine phosphate tablets are indicated for the management of mild to moderate pain, where treatment with an opioid is appropriate and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration, and persist over the course of therapy (see WARNINGS ), reserve opioid analgesics, including acetaminophen and codeine phosphate tablets, for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 212418

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 212418
ProductStrengthForm · routeLabelerProduct NDC
Acetaminophen and Codeine PhosphateAcetaminophen 300 mg/1; Codeine phosphate 30 mg/1TabletOralAdvanced Rx of Tennessee, LLC80425-0529
Acetaminophen and Codeine PhosphateAcetaminophen 300 mg/1; Codeine phosphate 60 mg/1TabletOralAdvanced Rx of Tennessee, LLC80425-0530
Acetaminophen and Codeine PhosphateAcetaminophen 300 mg/1; Codeine phosphate 30 mg/1TabletOralProficient Rx LP82804-283
Acetaminophen and Codeine PhosphateAcetaminophen 300 mg/1; Codeine phosphate 30 mg/1TabletOralNuCare Pharmaceuticals, Inc.68071-3798
Acetaminophen and Codeine PhosphateAcetaminophen 300 mg/1; Codeine phosphate 15 mg/1TabletOralElite Laboratories, Inc.64850-641
Acetaminophen and Codeine PhosphateAcetaminophen 300 mg/1; Codeine phosphate 30 mg/1TabletOralElite Laboratories, Inc.64850-642

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Acetaminophen and Codeine Phosphate NDC 64850-643 | Med-Code