NDC codes

FDA NDC Directory
Product NDC (as listed)64764-158Labeler and product segments. Claims need a package NDC.
Product NDC at billing width64764-0158Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
64764-158-1864764015818180 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (64764-158-18)Marketed from Aug 29, 2005
64764-158-41647640158414 CARTON in 1 TRAY (64764-158-41) / 1 BLISTER PACK in 1 CARTON / 7 TABLET, FILM COATED in 1 BLISTER PACKMarketed from Aug 29, 2005
64764-158-606476401586060 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (64764-158-60)Marketed from Aug 29, 2005

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Actoplus Met
Generic name (nonproprietary)
pioglitazone and metformin hydrochloride
Active ingredients
Pioglitazone hydrochloride — 15 mg/1Metformin hydrochloride — 850 mg/1
Dosage form
Tablet, Film coated
Route
Oral
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 021842
Marketing start
Listing expires
Other FDA classes
Biguanides (Chemical structure)Peroxisome Proliferator-activated Receptor alpha Agonists (Mechanism)Peroxisome Proliferator-activated Receptor gamma Agonists (Mechanism)Thiazolidinediones (Chemical structure)
Identifiers
Product ID 64764-158_8bacb433-92b6-4285-9ed3-b49e46ec63fcSPL ID 8bacb433-92b6-4285-9ed3-b49e46ec63fcSPL set ID 42e49120-6f3f-11db-9fe1-0800200c9a66RxCUI 861822, 861824UNII JQT35NPK6C, 786Z46389EUPC 0364764158606
Pharmacologic class
Biguanide; Peroxisome Proliferator Receptor alpha Agonist; Peroxisome Proliferator Receptor gamma Agonist; Thiazolidinedione

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N464764015818 followed by a unit qualifier and the quantity

Package 64764-0158-18. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

ACTOPLUS MET is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Limitations of Use ACTOPLUS MET is not recommended to treat type 1 diabetes mellitus or diabetic ketoacidosis. ACTOPLUS MET is a combination of pioglitazone, a thiazolidinedione agonist of peroxisome proliferator receptor gamma, and metformin hydrochloride (HCl), a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. ( 1 ) Limitations of Use : Not recommended for treatment of type 1 diabetes or diabetic ketoacidosis. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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