NDC codes

FDA NDC Directory
Product NDC (as listed)64380-778Labeler and product segments. Claims need a package NDC.
Product NDC at billing width64380-0778Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
64380-778-016438007780130 TABLET in 1 BOTTLE (64380-778-01)Marketed from Sep 1, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
tramadol hydrochloride
Generic name (nonproprietary)
tramadol hydrochloride
Active ingredients
Tramadol hydrochloride — 25 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 202075
Marketing start
Listing expires
DEA schedule
CIV
Other FDA classes
Full Opioid Agonists (Mechanism)
Identifiers
Product ID 64380-778_34384cff-f142-46cc-b5cb-ddc8b0f83f0eSPL ID 34384cff-f142-46cc-b5cb-ddc8b0f83f0eSPL set ID a6cbd5de-8ae5-49e3-b89b-e35536b115d8RxCUI 835603, 2670390UNII 9N7R477WCK
Pharmacologic class
Opioid Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N464380077801 followed by a unit qualifier and the quantity

Package 64380-0778-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

Tramadol hydrochloride tablets are indicated in adults for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose and death with opioids, which can occur at any dosage or duration and persist over the course of therapy [see Warnings and Precautions (5.2)] , reserve opioid analgesics including tramadol hydrochloride tablets for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain. Tramadol hydrochloride tablets are an opioid agonist indicated in…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 202075

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 202075
ProductStrengthForm · routeLabelerProduct NDC
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralProficient Rx LP82804-114
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralREMEDYREPACK INC.70518-4248
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralNuCare Pharmaceuticals, Inc.68071-3644
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralNuCare Pharmaceuticals,Inc.68071-3655
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralStrides Pharma Science Limited64380-791
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralNorthwind Health Company, LLC82868-052
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralBryant Ranch Prepack71335-2518
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralPreferred Pharmaceuticals Inc.68788-8717
tramadol hydrochlorideTramadol hydrochloride 50 mg/1TabletOralBryant Ranch Prepack71335-2612

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