NDC codes

FDA NDC Directory
Product NDC (as listed)58657-408Labeler and product segments. Claims need a package NDC.
Product NDC at billing width58657-0408Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
58657-408-0158657040801100 TABLET in 1 BOTTLE (58657-408-01)Marketed from Jun 15, 2024

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Esterified Estrogens And Methyltestosterone
Generic name (nonproprietary)
esterified estrogens, methyltestosterone
Active ingredients
Estrogens, Esterified — 1.25 mg/1Methyltestosterone — 2.5 mg/1
Dosage form
Tablet
Route
Oral
Product type
Prescription drug
Marketing category
Unapproved drug (other)
Marketing start
Listing expires
DEA schedule
CIII
Other FDA classes
Androgen Receptor Agonists (Mechanism)Androstanes (Chemical structure)
Identifiers
Product ID 58657-408_41b4ab92-44f0-da5f-e063-6394a90aa289SPL ID 41b4ab92-44f0-da5f-e063-6394a90aa289SPL set ID 1ab68a90-a2a6-b267-e063-6294a90ad751RxCUI 197670, 238006UNII 3ASP8Q3768, V9EFU16ZIFUPC 0358657408015
Pharmacologic class
Androgen

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N458657040801 followed by a unit qualifier and the quantity

Package 58657-0408-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE ESTERIFIED ESTROGENS AND METHYLTESTOSTERONE FULL STRENGTH and ESTERIFIED ESTROGENS AND METHYLTESTOSTERONE HALF STRENGTH are indicated in the treatment of: Moderate to severe vasomotor symptoms associated with the menopause in those patients not improved by estrogens alone. (There is no evidence that estrogens are effective for nervous symptoms or depression without associated vasomotor symptoms, and they should not be used to treat such conditions.) ESTERIFIED ESTROGENS AND METHYLTESTOSTERONE FULL STRENGTH and ESTERIFIED ESTROGENS AND METHYLTESTOSTERONE HALF STRENGTH HAVE NOT BEEN SHOWN TO BE EFFECTIVE FOR ANY PURPOSE DURING PREGNANCY AND ITS USE MAY CAUSE SEVERE HARM T…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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