What is NDC 53943-504?

53943-504 is the product NDC for Tussin CF, Dextromethorphan hydrobromide 10 mg/5mL + 2 more ingredients liquid, listed with the FDA by Discount Drug Mart. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Tussin CF (Dextromethorphan hydrobromide, Guaifenesin, Phenylephrine hydrochloride).

What is the active ingredient?

Dextromethorphan hydrobromide, Guaifenesin, Phenylephrine hydrochloride.

Discount Drug Mart, NDC labeler code 53943. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Tussin CF?

5 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Tussin CF NDC 53943-504 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)53943-504Labeler and product segments. Claims need a package NDC.

Product NDC at billing width53943-0504Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
53943-504-26	5394305042653943050426	237 mL in 1 BOTTLE (53943-504-26)Marketed from Nov 19, 2014

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Tussin CF
Generic name (nonproprietary): dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride
Active ingredients: Dextromethorphan hydrobromide — 10 mg/5mLGuaifenesin — 100 mg/5mLPhenylephrine hydrochloride — 5 mg/5mL
Dosage form: Liquid
Route: Oral
Labeler: Discount Drug MartNDC labeler code 53943
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 012
Marketing start: Nov 19, 2014
Listing expires: Dec 31, 2026
Other FDA classes: Adrenergic alpha1-Agonists (Mechanism)Decreased Respiratory Secretion Viscosity (Physiologic effect)Increased Respiratory Secretions (Physiologic effect)Sigma-1 Receptor Agonists (Mechanism)Uncompetitive NMDA Receptor Antagonists (Mechanism)
Identifiers: Product ID 53943-504_6af7fb23-9adb-4225-9773-c49ab6dd60d6SPL ID 6af7fb23-9adb-4225-9773-c49ab6dd60d6SPL set ID f8e7a08e-7422-4a1b-bfec-93e0b50d10cdRxCUI 1044949UNII 9D2RTI9KYH, 495W7451VQ, 04JA59TNSJ
Pharmacologic class: Expectorant; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist; alpha-1 Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N453943050426 followed by a unit qualifier and the quantity

Package 53943-0504-26. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 23, 2025.

Indications (excerpt from the label)

Uses help loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes temporarily relieves these symptoms occuring with a cold: nasal congestion cough due to minor throat and bronchial irritation

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 53943-504

What is NDC 53943-504?: 53943-504 is the product NDC for Tussin CF, Dextromethorphan hydrobromide 10 mg/5mL + 2 more ingredients liquid, listed with the FDA by Discount Drug Mart. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Tussin CF (Dextromethorphan hydrobromide, Guaifenesin, Phenylephrine hydrochloride).
What is the active ingredient?: Dextromethorphan hydrobromide, Guaifenesin, Phenylephrine hydrochloride.
Who is the labeler?: Discount Drug Mart, NDC labeler code 53943. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Tussin CF?: 5 other product NDCs are listed under this name. See all Tussin CF NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Tussin CF NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Tussin CFdextromethorphan hbr guaifenesin phenylephrine hcl	Dextromethorphan hydrobromide 20 mg/10mL + 2 more ingredients	LiquidOral	WinCo Foods, LLC	67091-470	67091-0470-04
Tussin CFdextromethorphan hbr guaifenesin phenylephrine hcl	Dextromethorphan hydrobromide 20 mg/10mL + 2 more ingredients	LiquidOral	WinCo Foods, LLC	67091-691	67091-0691-04
Tussin CFdextromethorphan hbr, guaifenesin, phenylephrine hcl	Dextromethorphan hydrobromide 20 mg/10mL + 2 more ingredients	LiquidOral	Best Choice (Valu Merchandisers Company)	63941-823	63941-0823-04
Tussin CFdextromethorphan hbr guaifenesin phenylephrine hcl	Dextromethorphan hydrobromide 20 mg/10mL + 2 more ingredients	SolutionOral	Strategic Sourcing Services	70677-1187	70677-1187-01
Tussin Cfdextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride	Dextromethorphan hydrobromide 10 mg/5mL + 2 more ingredients	LiquidOral	AptaPharma Inc.	76281-504	76281-0504-24

Other NDCs under M 012

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 012
Product	Strength	Form · route	Labeler	Product NDC
Daytime Cold and Flu Reliefacetaminohpen, dextromethorphan hbr, guaifenesin phenylephrine hcl	Acetaminophen 650 mg/30mL + 3 more ingredients	LiquidOral	The Kroger Co.	30142-722
Cold Fluacetaminophen, dextromethorphan hydrobromide, doxylamine succinate	—	Kit	HyVee Inc	42507-598
Allergy Reliefdiphenhydramine hcl	Diphenhydramine hydrochloride 25 mg/1	Tablet, Film coatedOral	H E B	37808-932
Medi First Plus Cherry Cough Dropsmenthol	Menthol 7.6 mg/1	LozengeOral	Unifirst First Aid Corporation	47682-915
Supress Adexbromopheniramine maleate, dextromethorphan hbr, phenylephrine hcl	Dexbrompheniramine maleate 1 mg/mL + 2 more ingredients	SyrupOral	Kramer Novis	52083-057
SAFETUSSIN Non Drowsy Cough plus chest congestiondextromethorphan hydrobromide, and guaifenesin	Dextromethorphan hydrobromide 10 mg/1; Guaifenesin 200 mg/1	TabletOral	KRAMER LABORATORIES	55505-231
Tusnel-DM Pediatricdextromethorphan hbr, guaifenesin, phenylephrine hcl	Dextromethorphan hydrobromide 2.5 mg/mL + 2 more ingredients	Solution/ dropsOral	LLORENS PHARMACEUTICALS INTERNATIONAL DIVISION	54859-606
Dg Health Cold Flu Reliefacetaminophen, dextromethorphan hydrobromide, doxylamine succinate	Acetaminophen 325 mg/15mL + 2 more ingredients	SolutionOral	Dolgencorp Inc	55910-753
Acetaminophen and Diphenhydramine citrate	Acetaminophen 500 mg/1; Diphenhydramine citrate 38 mg/1	TabletOral	InvaTech Pharma Solutions LLC	57631-010
MUCINEX SINUS-MAX SEVERE CONGESTION RELIEF SINUS and ALLERGYoxymetazoline hydrochloride	Oxymetazoline hydrochloride .05 g/100mL	SolutionNasal	Reckitt Benckiser LLC	63824-120
Vicks Sinex SEVERE CONGESTIONoxymetazoline hydrochloride	Oxymetazoline hydrochloride .0005 g/mL	SprayNasal	Procter & Gamble Manufacturing GmbH	64336-002
Walgreens Honey Lemon Cough Dropsmenthol	Menthol 7.5 mg/1	LozengeOral	Walgreens	0363-9959
Tesalon Jarabe Adultoacetaminophen, dextromethorphan hbr, guaifenesin usp, phenylephrine hcl	Acetaminophen 500 mg/20mL + 3 more ingredients	SyrupOral	OPMX LLC	69729-787
Guaifenesin	Guaifenesin 400 mg/1	TabletOral	Bryant Ranch Prepack	71335-9616
Cold Head Congestion Severeacetaminophen, guaifenesin, and phenylephrine hydrochloride	Acetaminophen 325 mg/1 + 2 more ingredients	Tablet, CoatedOral	Harris Teeter	72036-175
DG Health Cough Drops Cherry Flavormenthol	Menthol 5.8 mg/1	LozengeTopical	Dollar General Corporation	75712-005
Nuvicare NightTime Cold and Flu Softgelacetaminophen, dextromethorphan hydrobromide, doxylamine succinate	Acetaminophen 325 mg/1 + 2 more ingredients	Capsule, Liquid filledOral	NUVICARE LLC	84324-019
Quality Choice Mucus Reliefguaifenesin	Guaifenesin 400 mg/1	TabletOral	Chain Drug Marketing Association	83324-194
Diphenhydramine HCl	Diphenhydramine hydrochloride 12.5 mg/5mL	SolutionOral	Major Pharmaceuticals	0904-6985
severe cold and flu reliefacetaminophen, dextromethorphan hydrobromide, guaifenesin, phenylephrine hydrochloride	Acetaminophen 325 mg/15mL + 3 more ingredients	SolutionOral	Rite Aid Corporation	11822-3120

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