NDC codes

FDA NDC Directory
Product NDC (as listed)52536-006Labeler and product segments. Claims need a package NDC.
Product NDC at billing width52536-0006Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
52536-006-095253600060990 TABLET, FILM COATED in 1 BOTTLE (52536-006-09)Marketed from Apr 15, 2022

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
isosorbide dinitrate and hydralazine hydrochloride
Generic name (nonproprietary)
hydralazine hydrochloride and isosorbide dinitrate
Active ingredients
Hydralazine hydrochloride — 37.5 mg/1Isosorbide dinitrate — 20 mg/1
Dosage form
Tablet, Film coated
Route
Oral
Product type
Prescription drug
Marketing category
NDA authorized genericApplication NDA 020727
Marketing start
Listing expires
Other FDA classes
Arteriolar Vasodilation (Physiologic effect)Nitrates (Chemical structure)Vasodilation (Physiologic effect)
Identifiers
Product ID 52536-006_13386839-9eb4-4956-a788-d94a7b63cb77SPL ID 13386839-9eb4-4956-a788-d94a7b63cb77SPL set ID 620a0680-aad0-4923-84be-7393c0cbdcbdRxCUI 905377UNII FD171B778Y, IA7306519NUPC 0352536006095
Pharmacologic class
Arteriolar Vasodilator; Nitrate Vasodilator

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N452536000609 followed by a unit qualifier and the quantity

Package 52536-0006-09. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Isosorbide dinitrate and hydralazine hydrochloride tablets are a combination of isosorbide dinitrate, a nitrate vasodilator, and hydralazine hydrochloride, an arteriolar vasodilator, indicated for: the treatment of heart failure as an adjunct therapy to standard therapy in self-identified black patients to improve survival, prolong time to hospitalization for heart failure and to improve patient-reported functional status ( 1.1 ) Limitations of use: There is little experience in patients with NYHA class IV heart failure ( 1.2 ) 1.1 Treatment of Heart Failure in Self-identified Black Patients Isosorbide dinitrate and hydralazine hydrochloride tablets are indicated for the treatment of heart f…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 020727

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 020727
ProductStrengthForm · routeLabelerProduct NDC
BiDilhydralazine hydrochloride and isosorbide dinitrateHydralazine hydrochloride 37.5 mg/1; Isosorbide dinitrate 20 mg/1Tablet, Film coatedOralAzurity Pharmaceuticals, Inc.24338-010
isosorbide dinitrate and hydralazine hydrochloridehydralazine hydrochloride and isosorbide dinitrateHydralazine hydrochloride 37.5 mg/1; Isosorbide dinitrate 20 mg/1Tablet, Film coatedOralBryant Ranch Prepack72162-2343

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