What is NDC 52374-003?

52374-003 is the product NDC for Carbon Dioxide Compressed (carbon dioxide), Carbon dioxide 990 mL/L gas, listed with the FDA by MESSER GAS PUERTO RICO, INC. It has 4 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Carbon Dioxide Compressed (Carbon Dioxide).

MESSER GAS PUERTO RICO, INC, NDC labeler code 52374. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Carbon Dioxide Compressed?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Carbon Dioxide Compressed NDC 52374-003

NDC codes

FDA NDC Directory

Product NDC (as listed)52374-003Labeler and product segments. Claims need a package NDC.

Product NDC at billing width52374-0003Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
52374-003-01	52374000301	2.95 L in 1 CYLINDER (52374-003-01)Marketed from Jan 1, 1965
52374-003-02	52374000302	22.37 L in 1 CYLINDER (52374-003-02)Marketed from Jan 1, 1965
52374-003-03	52374000303	33.52 L in 1 CYLINDER (52374-003-03)Marketed from Jan 1, 1965
52374-003-04	52374000304	59 L in 1 CYLINDER (52374-003-04)Marketed from Jan 1, 1965

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Carbon Dioxide Compressed
Generic name (nonproprietary): carbon dioxide
Active ingredients: Carbon dioxide — 990 mL/L
Dosage form: Gas
Route: Respiratory (Inhalation)
Labeler: MESSER GAS PUERTO RICO, INCNDC labeler code 52374
Product type: Prescription drug
Marketing category: Unapproved medical gas
Marketing start: Jan 1, 1965
Listing expires: Dec 31, 2027
Other FDA classes: X-Ray Contrast Activity (Mechanism)
Identifiers: Product ID 52374-003_4af7058b-1f72-02cc-e063-6394a90a896dSPL ID 4af7058b-1f72-02cc-e063-6394a90a896dSPL set ID 91a75727-30c2-4c6f-88d9-0c3f423ed01eRxCUI 309004UNII 142M471B3J
Pharmacologic class: Radiographic Contrast Agent

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N452374000301 followed by a unit qualifier and the quantity

Package 52374-0003-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Feb 10, 2026.

Full label on DailyMed (opens in a new tab)

About NDC 52374-003

What is NDC 52374-003?: 52374-003 is the product NDC for Carbon Dioxide Compressed (carbon dioxide), Carbon dioxide 990 mL/L gas, listed with the FDA by MESSER GAS PUERTO RICO, INC. It has 4 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Carbon Dioxide Compressed (Carbon Dioxide).
What is the active ingredient?: Carbon dioxide.
Who is the labeler?: MESSER GAS PUERTO RICO, INC, NDC labeler code 52374. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Carbon Dioxide Compressed?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Carbon Dioxide Compressed (Carbon dioxide) NDC 52374-003