Letrozole NDC 51991-759

NDC codes

FDA NDC Directory

Product NDC (as listed)51991-759Labeler and product segments. Claims need a package NDC.

Product NDC at billing width51991-0759Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
51991-759-10	51991075910	1000 TABLET in 1 BOTTLE (51991-759-10)Marketed from Jun 4, 2011
51991-759-33	51991075933	30 TABLET in 1 BOTTLE (51991-759-33)Marketed from Jun 4, 2011
51991-759-90	51991075990	90 TABLET in 1 BOTTLE (51991-759-90)Marketed from Oct 1, 2022

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Letrozole
Generic name (nonproprietary): letrozole
Active ingredients: Letrozole — 2.5 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Breckenridge Pharmaceutical, Inc.
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 200161
Marketing start: Jun 4, 2011
Listing expires: Dec 31, 2027
Other FDA classes: Aromatase Inhibitors (Mechanism)
Identifiers: Product ID 51991-759_1bd709a7-993a-4e55-9bb5-d5f42678e7b9SPL ID 1bd709a7-993a-4e55-9bb5-d5f42678e7b9SPL set ID 63e54b62-a30d-4a56-9215-75e7a0b0bf02RxCUI 200064UNII 7LKK855W8IUPC 0351991759904
Pharmacologic class: Aromatase Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N451991075910 followed by a unit qualifier and the quantity

Package 51991-0759-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Aug 17, 2026.

Indications (excerpt from the label)

Letrozole tablets are an aromatase inhibitor indicated for: Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. ( 1.1 ) Extended adjuvant treatment of postmenopausal women with early breast cancer who have received prior standard adjuvant tamoxifen therapy. ( 1.2 ) First and second-line treatment of postmenopausal women with hormone receptor positive or unknown advanced breast cancer. ( 1.3 ) 1.1 Adjuvant Treatment of Early Breast Cancer Letrozole tablets are indicated for the adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. 1.2 Extended Adjuvant Treatment of Early Breast Cancer Letrozole tablets are ind…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 200161

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 200161
Product	Strength	Form · route	Labeler	Product NDC
Letrozole	Letrozole 2.5 mg/1	TabletOral	AvPAK	50268-476
Letrozole	Letrozole 2.5 mg/1	TabletOral	Natco Pharma Limited	63850-0025
Letrozole	Letrozole 2.5 mg/1	TabletOral	Bryant Ranch Prepack	71335-1526
Letrozole	Letrozole 2.5 mg/1	TabletOral	A-S Medication Solutions	50090-8002