NDC codes

FDA NDC Directory
Product NDC (as listed)51662-1588Labeler and product segments. Claims need a package NDC.
Product NDC at billing width51662-1588Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
51662-1588-35166215880325 POUCH in 1 CASE (51662-1588-3) / 1 VIAL, MULTI-DOSE in 1 POUCH (51662-1588-2) / 50 mL in 1 VIAL, MULTI-DOSEMarketed from Jul 11, 2022

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
BUPIVACAINE HCl
Generic name (nonproprietary)
bupivacaine hcl
Active ingredients
Bupivacaine hydrochloride — 5 mg/mL
Dosage form
Injection, Solution
Route
Perineural
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 018304
Marketing start
Listing expires
Other FDA classes
Amides (Chemical structure)Local Anesthesia (Physiologic effect)
Identifiers
Product ID 51662-1588_54ddbb1d-c786-9987-e063-6294a90adabdSPL ID 54ddbb1d-c786-9987-e063-6294a90adabdSPL set ID e391f807-7699-6d82-e053-2a95a90ab641RxCUI 1012396, 1012404UNII 7TQO7W3VT8
Pharmacologic class
Amide Local Anesthetic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N451662158803 followed by a unit qualifier and the quantity

Package 51662-1588-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS & USAGE Sensorcaine (bupivacaine HCl) is indicated for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. Only the 0.25% and 0.5% concentrations are indicated for obstetrical anesthesia (see WARNINGS ). Experience with nonobstetrical surgical procedures in pregnant patients is not sufficient to recommend use of the 0.75% concentration of bupivacaine HCl in these patients. Sensorcaine is not recommended for intravenous regional anesthesia (Bier Block) (see WARNINGS ). The routes of administration and indicated Sensorcaine concentrations are: See DOSAGE A…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 018304

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 018304
ProductStrengthForm · routeLabelerProduct NDC
Sensorcainebupivacaine hydrochlorideBupivacaine hydrochloride 2.5 mg/mLInjection, SolutionInfiltration, PerineuralHenry Schein, Inc.0404-9945
Sensorcainebupivacaine hydrochlorideBupivacaine hydrochloride 5 mg/mLInjection, SolutionPerineuralHenry Schein, Inc.0404-9947
BUPIVACAINE HClBupivacaine hydrochloride 2.5 mg/mLInjection, SolutionInfiltration, PerineuralHF Acquisition Co LLC, DBA HealthFirst51662-1592
Sensorcaine Mpfbupivacaine hydrochloride and epinephrine bitartrateBupivacaine hydrochloride 7.5 mg/mL; Epinephrine bitartrate .005 mg/mLInjection, SolutionEpidural, RetrobulbarFresenius Kabi USA, LLC63323-460
Sensorcaine Mpfbupivacaine hydrochlorideBupivacaine hydrochloride 2.5 mg/mLInjection, SolutionEpidural, Infiltration, Intracaudal, PerineuralFresenius Kabi USA, LLC63323-464
Sensorcaine Mpfbupivacaine hydrochloride and epinephrine bitartrateBupivacaine hydrochloride 5 mg/mL; Epinephrine bitartrate .005 mg/mLInjection, SolutionEpidural, Infiltration, Intracaudal, PerineuralFresenius Kabi USA, LLC63323-462
Sensorcaine Mpfbupivacaine hydrochloride and epinephrine bitartrateBupivacaine hydrochloride 5 mg/mL; Epinephrine bitartrate .005 mg/mLInjection, SolutionEpidural, Intracaudal, PerineuralFresenius Kabi USA, LLC63323-462
Sensorcainebupivacaine hydrochlorideBupivacaine hydrochloride 2.5 mg/mLInjection, SolutionInfiltration, PerineuralFresenius Kabi USA, LLC63323-465
Sensorcaine Mpfbupivacaine hydrochlorideBupivacaine hydrochloride 2.5 mg/mLInjection, SolutionEpidural, Infiltration, Intracaudal, PerineuralFresenius Kabi USA, LLC63323-464
Sensorcaine Mpfbupivacaine hydrochlorideBupivacaine hydrochloride 5 mg/mLInjection, SolutionEpidural, Infiltration, Intracaudal, PerineuralFresenius Kabi USA, LLC63323-466
Sensorcaine Mpfbupivacaine hydrochlorideBupivacaine hydrochloride 5 mg/mLInjection, SolutionEpidural, Intracaudal, PerineuralFresenius Kabi USA, LLC63323-466
Sensorcainebupivacaine hydrochlorideBupivacaine hydrochloride 5 mg/mLInjection, SolutionPerineuralFresenius Kabi USA, LLC63323-467

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