NDC codes

FDA NDC Directory
Product NDC (as listed)51660-566Labeler and product segments. Claims need a package NDC.
Product NDC at billing width51660-0566Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
51660-566-215166005662120 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-21)Marketed from Apr 1, 2022
51660-566-415166005664140 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-41)Marketed from Apr 1, 2022
51660-566-685166005666868 TABLET, EXTENDED RELEASE in 1 CARTON (51660-566-68)Marketed from Jan 17, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Guaifenesin
Generic name (nonproprietary)
guaifenesin
Active ingredients
Guaifenesin — 600 mg/1
Dosage form
Tablet, Extended release
Route
Oral
Product type
Over-the-counter drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 209254
Marketing start
Listing expires
Other FDA classes
Decreased Respiratory Secretion Viscosity (Physiologic effect)Increased Respiratory Secretions (Physiologic effect)
Identifiers
Product ID 51660-566_4aa4fb35-6f33-6e33-e063-6394a90a495eSPL ID 4aa4fb35-6f33-6e33-e063-6394a90a495eSPL set ID 7076e42a-17ff-4c42-9963-2dc02c0a5e49RxCUI 310621, 636522UNII 495W7451VQ
Pharmacologic class
Expectorant

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N451660056621 followed by a unit qualifier and the quantity

Package 51660-0566-21. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Uses Helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bronchial mucus and make coughs more productive

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 209254

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 209254
ProductStrengthForm · routeLabelerProduct NDC
Guaifenesin Extended ReleaseguaifenesinGuaifenesin 1200 mg/1Tablet, Extended releaseOralSAM'S WEST INC68196-996
GuaifenesinGuaifenesin 600 mg/1Tablet, Extended releaseOralAMERISOURCE BERGEN46122-750
GuaifenesinGuaifenesin 1200 mg/1Tablet, Extended releaseOralOhm Laboratories, Inc.51660-567
GuaifenesinGuaifenesin 600 mg/1Tablet, Extended releaseOralKroger Company30142-961
Guaifenesin Extended ReleaseguaifenesinGuaifenesin 1200 mg/1Tablet, Extended releaseOralKroger Company30142-962
GuaifenesinGuaifenesin 600 mg/1Tablet, Extended releaseOralWalmart Stores, Inc.79903-124
GuaifenesinGuaifenesin 600 mg/1Tablet, Extended releaseOralCVS51316-071
GuaifenesinGuaifenesin 600 mg/1Tablet, Extended releaseOralPublix Super Markets, Inc41415-996
Guaifenesin Extended ReleaseguaifenesinGuaifenesin 1200 mg/1Tablet, Extended releaseOralPUBLIX SUPER MARKETS, INC41415-997

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