Metformin Hydrochloride NDC 51655-559

NDC codes

FDA NDC Directory

Product NDC (as listed)51655-559Labeler and product segments. Claims need a package NDC.

Product NDC at billing width51655-0559Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
51655-559-25	51655055925	60 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (51655-559-25)Marketed from Dec 12, 2023
51655-559-26	51655055926	90 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (51655-559-26)Marketed from Oct 12, 2023
51655-559-52	51655055952	30 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (51655-559-52)Marketed from Oct 25, 2023
51655-559-82	51655055982	120 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (51655-559-82)Marketed from Oct 11, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Metformin Hydrochloride
Generic name (nonproprietary): metformin hydrochloride
Active ingredients: Metformin hydrochloride — 500 mg/1
Dosage form: Tablet, Extended release
Route: Oral
Labeler: Northwind Health Company, LLC
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 201991
Marketing start: Oct 11, 2023
Listing expires: Dec 31, 2027
Other FDA classes: Biguanides (Chemical structure)
Identifiers: Product ID 51655-559_4a2aee29-b25b-bc57-e063-6394a90a55f6SPL ID 4a2aee29-b25b-bc57-e063-6394a90a55f6SPL set ID 07d8a69f-30d9-7511-e063-6394a90a95caRxCUI 860975UNII 786Z46389E
Pharmacologic class: Biguanide

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N451655055925 followed by a unit qualifier and the quantity

Package 51655-0559-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 1, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

Metformin hydrochloride extended-release tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Metformin hydrochloride extended-release tablets are a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 201991

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 201991
Product	Strength	Form · route	Labeler	Product NDC
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	QPharma Inc	42708-201
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	Aphena Pharma Solutions - Tennessee, LLC	71610-837
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	A-S Medication Solutions	50090-7116
Metformin Hydrochloride ERmetformin hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	Leading Pharma, LLC	69315-410
Metformin hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	Proficient Rx LP	63187-779
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	PD-Rx Pharmaceuticals, Inc.	72789-400
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	NCS HealthCare of KY, LLC dba Vangard Labs	0615-8289
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	Preferred Pharmaceuticals Inc.	68788-8814
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	Ascend Laboratories, LLC	67877-159
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	PD-Rx Pharmaceuticals, Inc.	72789-455
Metformin hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	NuCare Pharmaceuticals, Inc.	68071-1419
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	A-S Medication Solutions	50090-1494
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	A-S Medication Solutions	50090-7579
Metformin Hydrochloride	Metformin hydrochloride 500 mg/1	Tablet, Extended releaseOral	Bryant Ranch Prepack	71335-0886