Over-the-counter drug · OTC MONOGRAPH DRUG

Low Dose Aspirin (Aspirin) NDC 51316-456

Aspirin 81 mg/1 · Tablet, Delayed release · Oral · CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED

NDC codes

FDA NDC Directory
Product NDC (as listed)51316-456Labeler and product segments. Claims need a package NDC.
Product NDC at billing width51316-0456Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
51316-456-5151316045651365 TABLET, DELAYED RELEASE in 1 BOTTLE, PLASTIC (51316-456-51)Marketed from Oct 2, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Low Dose Aspirin
Generic name (nonproprietary)
aspirin
Active ingredients
Aspirin — 81 mg/1
Dosage form
Tablet, Delayed release
Route
Oral
Product type
Over-the-counter drug
Marketing category
OTC monograph drugApplication M 013
Marketing start
Listing expires
Other FDA classes
Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)Decreased Platelet Aggregation (Physiologic effect)Decreased Prostaglandin Production (Physiologic effect)
Identifiers
Product ID 51316-456_f96d919a-e06f-4d44-807f-0ac29999334dSPL ID f96d919a-e06f-4d44-807f-0ac29999334dSPL set ID 8bc75bcf-01c9-41d0-a96f-77a24e3edf01RxCUI 308416UNII R16CO5Y76E
Pharmacologic class
Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N451316045651 followed by a unit qualifier and the quantity

Package 51316-0456-51. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Uses for the temporary relief of minor aches and pains or as recommended by your doctor

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 51316-456

What is NDC 51316-456?
51316-456 is the product NDC for Low Dose Aspirin (aspirin), Aspirin 81 mg/1 tablet, delayed release, listed with the FDA by CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Low Dose Aspirin (Aspirin).
What is the active ingredient?
Aspirin.
Who is the labeler?
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED, NDC labeler code 51316. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Low Dose Aspirin?
31 other product NDCs are listed under this name. See all Low Dose Aspirin NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Low Dose Aspirin NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, Delayed releaseOralPinnacle RX LLC87438-000387438-0003-01
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, Delayed releaseOralFamora Inc.87509-098187509-0981-05
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralHy-Vee42507-00642507-0006-1242507-0006-50
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, Delayed releaseOralBJWC (Berkley & Jensen / BJ's)68391-48168391-0481-93
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralAkron Pharma Inc.71399-101471399-1014-0171399-1014-0271399-1014-04+1 more
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralWalmart Inc.79903-48179903-0481-1179903-0481-50
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralSAM'S WEST INC68196-48168196-0481-70
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralTopco Associates76162-98076162-0980-0576162-0980-1276162-0980-50
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralAmerisourceBergen (Good Neighbor Pharmacy) 4612246122-76146122-0761-5846122-0761-61
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralStrategic Sourcing Services LLC70677-115070677-1150-0170677-1150-0270677-1150-03

All 32 Low Dose Aspirin NDCs

Other NDCs under M 013

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 013
ProductStrengthForm · routeLabelerProduct NDC
Best Choice Effervescent Pain Reliever 36aspirinAspirin 325 mg/1Tablet, EffervescentOralVALU MERCHANDISERS COMPANY63941-241
Aspirin PacksaspirinAspirin 325 mg/1Tablet, Film coatedOralSina Health Inc70385-2006
Back and Body Extra Strengthaspirin, caffeineAspirin 500 mg/1; Caffeine 32.5 mg/1Tablet, Film coatedOralCardinal Health 110, LLC. DBA Leader70000-0127
foster and thrive aspirinaspirinAspirin 81 mg/1Tablet, ChewableOralStrategic Sourcing Services LLC70677-1134
Medique Pain Offacetaminophen, aspirin, caffeineCaffeine 65 mg/1 + 2 more ingredientsTablet, Film coatedOralUnifirst First Aid Corporation47682-238
Acetaminophen Extra StrengthacetaminophenAcetaminophen 500 mg/1Tablet, Film coatedOralWal-Mart Stores Inc49035-175
Low Dose AspirinaspirinAspirin 81 mg/1Tablet, CoatedOralA-S Medication Solutions50090-4830
Childrens Pain ReliefAcetaminophen 160 mg/5mLLiquidOralAllegiant Health69168-455
Aspirin Low DoseaspirinAspirin 81 mg/1Tablet, CoatedOralMAJOR PHARMACEUTICALS0904-6783
equaline acetaminophenacetaminophenAcetaminophen 500 mg/1TabletOralUnited Natural Foods, Inc. dba UNFI41163-363
Chewable AspirinaspirinAspirin 81 mg/1Tablet, ChewableOralHARRIS TEETER72036-205
Pain Relief PM Extra Strengthacetaminophen and diphenhydramine hydrochlorideAcetaminophen 500 mg/1; Diphenhydramine hydrochloride 25 mg/1Tablet, CoatedOralChain Drug Marketing Association63868-325
Excedrin Extra Strength and Excedrin Tension Headacheacetaminophen, aspirin (nsaid), and caffeine—KitHaleon US Holdings LLC0067-8151
Enteric Coated Aspirin Regular StrengthaspirinAspirin 325 mg/1Tablet, Delayed releaseOralSafeway21130-081
Headache Relief Extra Strengthacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralH E B37808-586
DrKids Childrens Pain and Feveracetaminophen 80mg/pieceAcetaminophen 80 mg/1Bar, ChewableOralCalmCo LLC73282-2480
CAREALL Non-Aspirin PM Extra Strengthacetaminophen, diphenhydramine hclAcetaminophen 500 mg/1; Diphenhydramine hydrochloride 25 mg/1TabletOralNew World Imports, Inc51824-069
dg health pain reliefacetaminophenAcetaminophen 500 mg/1TabletOralDolgencorp Inc55910-661
Extra Strength AcetaminophenacetaminophenAcetaminophen 500 mg/1TabletOralPreferred Pharmaceuticals Inc.68788-4065
Aspirin 81mg Dye-Freeaspirin 81mgAspirin 81 mg/1Tablet, Film coatedOralAllegiant Health69168-457

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