Leucovorin Calcium NDC 50742-184

NDC codes

FDA NDC Directory

Product NDC (as listed)50742-184Labeler and product segments. Claims need a package NDC.

Product NDC at billing width50742-0184Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
50742-184-25	50742018425	25 TABLET in 1 BOTTLE (50742-184-25)Marketed from Jul 30, 2020

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Leucovorin Calcium
Generic name (nonproprietary): leucovorin calcium
Active ingredients: Leucovorin calcium — 25 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Ingenus Pharmaceuticals, LLC
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 211132
Marketing start: Jul 30, 2020
Listing expires: Dec 31, 2027
Other FDA classes: Folic Acid (Chemical structure)
Identifiers: Product ID 50742-184_93e939b7-2201-442a-a2be-7c5804f8be6fSPL ID 93e939b7-2201-442a-a2be-7c5804f8be6fSPL set ID 7409cdee-9093-47af-a4c4-2c55ce1b6361RxCUI 197860, 197861, 197862, 197863UNII RPR1R4C0P4UPC 0350742182244, 0350742182121, 0350742183241, 0350742184255, 0350742181308, 0350742181018
Pharmacologic class: Folate Analog

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N450742018425 followed by a unit qualifier and the quantity

Package 50742-0184-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 18, 2026.

Indications (excerpt from the label)

Leucovorin calcium tablets are a folate analog indicated: To reduce the toxicity of: Methotrexate in adult patients with impaired methotrexate elimination, and Folic acid antagonists or dihydrofolate reductase (DHFR) inhibitors following an overdose in adult patients. ( 1.1 ) For the treatment of cerebral folate transport deficiency in adult and pediatric patients who have a confirmed variant in the folate receptor 1 gene (FOLR1-CFTD). ( 1.2 ) Limitations of Use Leucovorin calcium tablets are not recommended for use in patients with a deficiency of methenyltetrahydrofolate synthetase (MTHFS) because MTHFS is a primary enzyme in the metabolism of leucovorin to 5-methenyltetrahydrofolate. ( 1.…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 211132

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 211132
Product	Strength	Form · route	Labeler	Product NDC
Leucovorin Calcium	Leucovorin calcium 5 mg/1	TabletOral	Ingenus Pharmaceuticals, LLC	50742-181
Leucovorin Calcium	Leucovorin calcium 10 mg/1	TabletOral	Ingenus Pharmaceuticals, LLC	50742-182
Leucovorin Calcium	Leucovorin calcium 15 mg/1	TabletOral	Ingenus Pharmaceuticals, LLC	50742-183
Leucovorin Calcium	Leucovorin calcium 25 mg/1	TabletOral	Major Pharmaceuticals	0904-7584