NDC codes

FDA NDC Directory
Product NDC (as listed)50242-125Labeler and product segments. Claims need a package NDC.
Product NDC at billing width50242-0125Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
50242-125-01502420125011 VIAL, SINGLE-DOSE in 1 CARTON (50242-125-01) / 2.5 mL in 1 VIAL, SINGLE-DOSEMarketed from Jun 15, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Columvi
Generic name (nonproprietary)
glofitamab
Active ingredients
Glofitamab — 2.5 mg/2.5mL
Dosage form
Solution, Concentrate
Route
Intravenous
Labeler
Genentech, Inc.NDC labeler code 50242
Product type
Prescription drug
Marketing category
BLA — Biologics License ApplicationApplication BLA 761309
Marketing start
Listing expires
Other FDA classes
CD20-directed Antibody Interactions (Mechanism)CD3 Receptor Agonists (Mechanism)CD3-directed Antibody Interactions (Mechanism)Cytochrome P450 Inhibitors (Mechanism)Increased Cytokine Activity (Physiologic effect)
Identifiers
Product ID 50242-125_33693fc1-cb24-4ce6-8ceb-b34ebf3536c0SPL ID 33693fc1-cb24-4ce6-8ceb-b34ebf3536c0SPL set ID 3516e753-f064-4d30-9bd5-e3f2e143f75dRxCUI 2639786, 2639792, 2639794, 2639795UNII 06P3KLK2J8
Pharmacologic class
Bispecific CD20-directed CD3 T Cell Engager

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N450242012501 followed by a unit qualifier and the quantity

Package 50242-0125-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

COLUMVI is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS) or large B-cell lymphoma (LBCL) arising from follicular lymphoma, after two or more lines of systemic therapy. This indication is approved under accelerated approval based on response rate and durability of response [see Clinical Studies (14.1) ] . Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). COLUMVI is a bispecific CD20-directed CD3 T-cell engager indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphom…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 50242-125

What is NDC 50242-125?
50242-125 is the product NDC for Columvi (glofitamab), Glofitamab 2.5 mg/2.5mL solution, concentrate, listed with the FDA by Genentech, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Columvi (Glofitamab).
What is the active ingredient?
Glofitamab.
Who is the labeler?
Genentech, Inc., NDC labeler code 50242. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Columvi?
1 other product NDC are listed under this name. See all Columvi NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Columvi NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
ColumviglofitamabGlofitamab 10 mg/10mLConcentrateIntravenousGenentech, Inc.50242-12750242-0127-01

Other NDCs under BLA 761309

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under BLA 761309
ProductStrengthForm · routeLabelerProduct NDC
ColumviglofitamabGlofitamab 10 mg/10mLConcentrateIntravenousGenentech, Inc.50242-127

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