Carbidopa and Levodopa NDC 50228-459

NDC codes

FDA NDC Directory

Product NDC (as listed)50228-459Labeler and product segments. Claims need a package NDC.

Product NDC at billing width50228-0459Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
50228-459-01	50228045901	100 TABLET in 1 BOTTLE (50228-459-01)Marketed from May 7, 2021
50228-459-05	50228045905	500 TABLET in 1 BOTTLE (50228-459-05)Marketed from May 7, 2021
50228-459-10	50228045910	1000 TABLET in 1 BOTTLE (50228-459-10)Marketed from May 7, 2021
50228-459-30	50228045930	30 TABLET in 1 BOTTLE (50228-459-30)Marketed from May 7, 2021

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Carbidopa and Levodopa
Generic name (nonproprietary): carbidopa and levodopa
Active ingredients: Carbidopa — 25 mg/1Levodopa — 250 mg/1
Dosage form: Tablet
Route: Oral
Labeler: ScieGen Pharmaceuticals Inc
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 214092
Marketing start: May 7, 2021
Listing expires: Dec 31, 2027
Other FDA classes: Aromatic (Chemical structure)
Identifiers: Product ID 50228-459_3b66d16c-654c-4dcb-ad04-3503aa7f1ca5SPL ID 3b66d16c-654c-4dcb-ad04-3503aa7f1ca5SPL set ID a32afa84-7bc0-4bd3-bc50-55d738f3d7ceRxCUI 197443, 197444, 197445UNII 46627O600J, MNX7R8C5VOUPC 0350228458054, 0350228459303, 0350228459051, 0350228458016, 0350228459013, 0350228457057, 0350228458108, 0350228457019, 0350228458306, 0350228457309
Pharmacologic class: Aromatic Amino Acid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N450228045901 followed by a unit qualifier and the quantity

Package 50228-0459-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 27, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE Carbidopa and levodopa tablets are indicated in the treatment of Parkinson's disease, post-encephalitic parkinsonism, and symptomatic parkinsonism that may follow carbon monoxide intoxication or manganese intoxication. Carbidopa allows patients treated for Parkinson's disease to use much lower doses of levodopa. Some patients who responded poorly to levodopa have improved on carbidopa and levodopa tablets. This is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous system. Carbidopa has not been shown to enhance the intrinsic efficacy of levodopa. Carbidopa …

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 214092

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 214092
Product	Strength	Form · route	Labeler	Product NDC
Carbidopa and Levodopa	Carbidopa 10 mg/1; Levodopa 100 mg/1	TabletOral	Westminster Pharmaceuticals, LLC	69367-338
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	Westminster Pharmaceuticals, LLC	69367-339
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 250 mg/1	TabletOral	Westminster Pharmaceuticals, LLC	69367-340
Carbidopa and Levodopa	Carbidopa 10 mg/1; Levodopa 100 mg/1	TabletOral	Proficient Rx LP	71205-877
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	A-S Medication Solutions	50090-6725
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	Proficient Rx LP	71205-878
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 250 mg/1	TabletOral	Proficient Rx LP	71205-879
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	A-S Medication Solutions	50090-5969
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 250 mg/1	TabletOral	Coupler LLC	67046-1450
Carbidopa and Levodopa	Carbidopa 10 mg/1; Levodopa 100 mg/1	TabletOral	A-S Medication Solutions	50090-7186
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	Aphena Pharma Solutions - Tennessee, LLC	71610-647
Carbidopa and Levodopa	Carbidopa 10 mg/1; Levodopa 100 mg/1	TabletOral	ScieGen Pharmaceuticals Inc	50228-457
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	ScieGen Pharmaceuticals Inc	50228-458
Carbidopa and Levodopa	Carbidopa 25 mg/1; Levodopa 100 mg/1	TabletOral	A-S Medication Solutions	50090-6580