What is NDC 49281-915?

49281-915 is the product NDC for Yf-Vax, Yellow fever virus strain 17d-204 live antigen 4.74 [PFU]/.5mL injection, powder, lyophilized, for suspension, listed with the FDA by Sanofi Vaccines US Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Yf-Vax (Yellow fever virus strain 17d-204 live antigen).

What is the active ingredient?

Yellow fever virus strain 17d-204 live antigen.

Sanofi Vaccines US Inc., NDC labeler code 49281. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Yf-Vax?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Yf-Vax NDC 49281-915 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)49281-915Labeler and product segments. Claims need a package NDC.

Product NDC at billing width49281-0915Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
49281-915-01	4928109150149281091501	5 VIAL, SINGLE-DOSE in 1 PACKAGE (49281-915-01) / .5 mL in 1 VIAL, SINGLE-DOSE (49281-915-58)Marketed from May 22, 1953
49281-915-05	4928109150549281091505	1 VIAL, MULTI-DOSE in 1 PACKAGE (49281-915-05) / 2.5 mL in 1 VIAL, MULTI-DOSE (49281-915-68)Marketed from May 22, 1953

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Yf-Vax
Generic name (nonproprietary): yellow fever virus strain 17d-204 live antigen
Active ingredients: Yellow fever virus strain 17d-204 live antigen — 4.74 [PFU]/.5mL
Dosage form: Injection, Powder, Lyophilized, For suspension
Route: Subcutaneous
Labeler: Sanofi Vaccines US Inc.NDC labeler code 49281
Product type: Vaccine
Marketing category: BLA — Biologics License ApplicationApplication BLA 103915
Marketing start: May 22, 1953
Listing expires: Dec 31, 2027
Other FDA classes: Actively Acquired Immunity (Physiologic effect)Attenuated (Chemical structure)Yellow Fever Vaccine (Chemical structure)
Identifiers: Product ID 49281-915_619c17f6-1c56-4821-9ce4-cfdd5d381d86SPL ID 619c17f6-1c56-4821-9ce4-cfdd5d381d86
Pharmacologic class: Live Attenuated Yellow Fever Virus Vaccine

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Immunization administration (CPT 90460–90474)

Giving a vaccine is reported separately from the vaccine product code, with an immunization administration code. Which code applies depends on the patient's age, the route and whether counselling was provided.

How CPT relates to drug billing

NDC on a medical claim

N449281091501 followed by a unit qualifier and the quantity

Package 49281-0915-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 49281-915

What is NDC 49281-915?: 49281-915 is the product NDC for Yf-Vax, Yellow fever virus strain 17d-204 live antigen 4.74 [PFU]/.5mL injection, powder, lyophilized, for suspension, listed with the FDA by Sanofi Vaccines US Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Yf-Vax (Yellow fever virus strain 17d-204 live antigen).
What is the active ingredient?: Yellow fever virus strain 17d-204 live antigen.
Who is the labeler?: Sanofi Vaccines US Inc., NDC labeler code 49281. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Yf-Vax?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under BLA 103915

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under BLA 103915
Product	Strength	Form · route	Labeler	Product NDC
Diluentsodium chloride	Sodium chloride 4.5 mg/.5mL	InjectionSubcutaneous	Sanofi Vaccines US Inc.	49281-912