What is NDC 46123-539?

46123-539 is the product NDC for Carbon Dioxide-Oxygen-Nitrogen Mixture, Oxygen 450 mL/L; Carbon dioxide 50 mL/L gas, listed with the FDA by Roberts Oxygen Company, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.

Roberts Oxygen Company, Inc., NDC labeler code 46123. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Carbon Dioxide-Oxygen-Nitrogen Mixture?

6 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Carbon Dioxide-Oxygen-Nitrogen Mixture NDC 46123-539

NDC codes

FDA NDC Directory

Product NDC (as listed)46123-539Labeler and product segments. Claims need a package NDC.

Product NDC at billing width46123-0539Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
46123-539-01	46123053901	2100 L in 1 CYLINDER (46123-539-01)Marketed from Jan 1, 1966
46123-539-02	46123053902	6169 L in 1 CYLINDER (46123-539-02)Marketed from Jan 1, 1966

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Carbon Dioxide-Oxygen-Nitrogen Mixture
Generic name (nonproprietary): carbon dioxide-oxygen-nitrogen mixture
Active ingredients: Oxygen — 450 mL/LCarbon dioxide — 50 mL/L
Dosage form: Gas
Route: Respiratory (Inhalation)
Labeler: Roberts Oxygen Company, Inc.NDC labeler code 46123
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 205849
Marketing start: Jan 1, 1966
Listing expires: Dec 31, 2026
Other FDA classes: X-Ray Contrast Activity (Mechanism)
Identifiers: Product ID 46123-539_43ced7fd-cce5-9ef3-e063-6294a90a09cdSPL ID 43ced7fd-cce5-9ef3-e063-6294a90a09cdSPL set ID 2becaa34-d392-6b84-e063-6394a90a1597RxCUI 999651UNII S88TT14065, 142M471B3J
Pharmacologic class: Radiographic Contrast Agent

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N446123053901 followed by a unit qualifier and the quantity

Package 46123-0539-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Nov 17, 2025.

Full label on DailyMed (opens in a new tab)

About NDC 46123-539

What is NDC 46123-539?: 46123-539 is the product NDC for Carbon Dioxide-Oxygen-Nitrogen Mixture, Oxygen 450 mL/L; Carbon dioxide 50 mL/L gas, listed with the FDA by Roberts Oxygen Company, Inc.. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Carbon Dioxide-Oxygen-Nitrogen Mixture.
What is the active ingredient?: Oxygen, Carbon dioxide.
Who is the labeler?: Roberts Oxygen Company, Inc., NDC labeler code 46123. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Carbon Dioxide-Oxygen-Nitrogen Mixture?: 6 other product NDCs are listed under this name. See all Carbon Dioxide-Oxygen-Nitrogen Mixture NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Carbon Dioxide-Oxygen-Nitrogen Mixture NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Carbon Dioxide-Oxygen-Nitrogen Mixture	Oxygen 350 mL/L; Carbon dioxide 50 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-537	46123-0537-01
Carbon Dioxide-Oxygen-Nitrogen Mixture	Oxygen 50 mL/L; Carbon dioxide 200 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-535	46123-0535-0146123-0535-0246123-0535-03
Carbon Dioxide-Oxygen-Nitrogen Mixture	Oxygen 210 mL/L; Carbon dioxide 70 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-536	46123-0536-0146123-0536-02
Carbon Dioxide-Oxygen-Nitrogen Mixture	Oxygen 250 mL/L; Carbon dioxide 100 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-541	46123-0541-0146123-0541-02
Carbon Dioxide-Oxygen-Nitrogen Mixture	Oxygen 400 mL/L; Carbon dioxide 50 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-538	46123-0538-01
Carbon Dioxide-Oxygen-Nitrogen Mixture	Oxygen 330 mL/L; Carbon dioxide 70 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-540	46123-0540-01

Other NDCs under NDA 205849

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 205849
Product	Strength	Form · route	Labeler	Product NDC
Carbon Dioxide-Oxygen Mixture	Carbon dioxide 200 mL/L; Oxygen 800 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-124
Oxygen	Oxygen 990 mL/L	GasRespiratory (Inhalation)	HOWARDS MEDICAL LLC	72973-001
Carbon Dioxide-Air Mixture	Carbon dioxide 100 mL/L; Oxygen 210 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-181
Oxygen	Oxygen 99 L/100L	GasRespiratory (Inhalation)	Childrens Hospital of Philadelphia	43734-001
Oxygen	Oxygen 99 L/100L	GasRespiratory (Inhalation)	South Jersey Welding Supply	11056-001
Oxygen	Oxygen 990 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-001
Oxygen	Oxygen 990 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-002
Oxygen	Oxygen 990 mL/L	GasRespiratory (Inhalation)	Oxarc, LLC	34057-001
Carbon Dioxide-Air Mixture	Carbon dioxide 70 mL/L; Oxygen 210 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-016
Carbon Dioxide-Air Mixture	Carbon dioxide 50 mL/L; Oxygen 210 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-115
Oxygen	Oxygen 990 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-045
Air	Oxygen 210 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-109
Carbon Dioxide-Oxygen Mixture	Carbon dioxide 150 mL/L; Oxygen 850 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-123
Carbon Dioxide-Air Mixture	Carbon dioxide 80 mL/L; Oxygen 210 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-117
Carbon Dioxide-Oxygen Mixture	Carbon dioxide 70 mL/L; Oxygen 930 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-120
Oxygen	Oxygen 990 mL/L	GasRespiratory (Inhalation)	Oxygen Service Company, Inc	49696-100
Carbon Dioxide-Oxygen Mixture	Oxygen 880 mL/L; Carbon dioxide 120 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-522
Oxygen-Helium Mixture	Oxygen 400 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-514
Carbon Dioxide-Oxygen Mixture	Carbon dioxide 100 mL/L; Oxygen 900 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-521
Oxygen-Nitrogen Mixture	Oxygen 300 mL/L	GasRespiratory (Inhalation)	Roberts Oxygen Company, Inc.	46123-529

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