NDC codes

FDA NDC Directory
Product NDC (as listed)45963-438Labeler and product segments. Claims need a package NDC.
Product NDC at billing width45963-0438Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
45963-438-6445963043864473 mL in 1 BOTTLE (45963-438-64)Marketed from Feb 28, 2011

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Enulose
Generic name (nonproprietary)
lactulose
Active ingredients
Lactulose — 10 g/15mL
Dosage form
Solution
Route
Oral, Rectal
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 090502
Marketing start
Listing expires
Other FDA classes
Acidifying Activity (Mechanism)Osmotic Activity (Mechanism)Stimulation Large Intestine Fluid/Electrolyte Secretion (Physiologic effect)
Identifiers
Product ID 45963-438_bda4ccaa-fa33-4911-b3bd-12391c365f47SPL ID bda4ccaa-fa33-4911-b3bd-12391c365f47SPL set ID 00c42c5c-d19e-4130-aa08-a8bbd47d3e5bRxCUI 391937, 755470UNII 9U7D5QH5AE
Pharmacologic class
Osmotic Laxative

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N445963043864 followed by a unit qualifier and the quantity

Package 45963-0438-64. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

INDICATIONS AND USAGE For the prevention and treatment of portal-systemic encephalopathy, including the stages of hepatic pre-coma and coma. Controlled studies have shown that lactulose solution therapy reduces the blood ammonia levels by 25 to 50%; this is generally paralleled by an improvement in the patients' mental state and by an improvement in EEG patterns. The clinical response has been observed in about 75% of patients, which is at least as satisfactory as that resulting from neomycin therapy. An increase in patients' protein tolerance is also frequently observed with lactulose therapy. In the treatment of chronic portal-systemic encephalopathy, Lactulose has been given for over 2 ye…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 090502

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 090502
ProductStrengthForm · routeLabelerProduct NDC
EnuloselactuloseLactulose 10 g/15mLSolutionOral, RectalBryant Ranch Prepack63629-8800
LactuloseLactulose 10 g/15mLSolutionOral, RectalFresenius Kabi Austria GmbH18124-002

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