What is NDC 43066-142?

43066-142 is the product NDC for naloxone hydrochloride, Naloxone hydrochloride 1 mg/mL injection, solution, listed with the FDA by Baxter Healthcare Corporation. It has 1 package NDC, shown above in 10- and 11-digit form.

Baxter Healthcare Corporation, NDC labeler code 43066. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for naloxone hydrochloride?

77 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

naloxone hydrochloride NDC 43066-142 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)43066-142Labeler and product segments. Claims need a package NDC.

Product NDC at billing width43066-0142Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
43066-142-10	43066014210	10 CARTON in 1 CARTON (43066-142-10) / 1 SYRINGE, GLASS in 1 CARTON (43066-142-01) / 2 mL in 1 SYRINGE, GLASSMarketed from Jun 3, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): naloxone hydrochloride
Generic name (nonproprietary): naloxone hydrochloride
Active ingredients: Naloxone hydrochloride — 1 mg/mL
Dosage form: Injection, Solution
Route: Intramuscular, Intravenous, Subcutaneous
Labeler: Baxter Healthcare CorporationNDC labeler code 43066
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 214785
Marketing start: Jun 3, 2025
Listing expires: Dec 31, 2026
Other FDA classes: Opioid Antagonists (Mechanism)
Identifiers: Product ID 43066-142_48137634-91d7-41e3-b54b-e4321d69668aSPL ID 48137634-91d7-41e3-b54b-e4321d69668aSPL set ID 48137634-91d7-41e3-b54b-e4321d69668aRxCUI 1191250UNII F850569PQR
Pharmacologic class: Opioid Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N443066014210 followed by a unit qualifier and the quantity

Package 43066-0142-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Oct 4, 2024.

Indications (excerpt from the label)

INDICATIONS AND USAGE Naloxone hydrochloride injection is indicated for the complete or partial reversal of opioid depression, including respiratory depression, induced by natural and synthetic opioids, including propoxyphene, methadone and certain mixed agonist-antagonist analgesics: nalbuphine, pentazocine, butorphanol, and cyclazocine. Naloxone hydrochloride injection is also indicated for diagnosis of suspected or known acute opioid overdosage. Naloxone hydrochloride injection may be useful as an adjunctive agent to increase blood pressure in the management of septic shock (see CLINICAL PHARMACOLOGY; Adjunctive Use in Septic Shock ).

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 43066-142

What is NDC 43066-142?: 43066-142 is the product NDC for naloxone hydrochloride, Naloxone hydrochloride 1 mg/mL injection, solution, listed with the FDA by Baxter Healthcare Corporation. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: naloxone hydrochloride.
What is the active ingredient?: Naloxone hydrochloride.
Who is the labeler?: Baxter Healthcare Corporation, NDC labeler code 43066. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for naloxone hydrochloride?: 77 other product NDCs are listed under this name. See all naloxone hydrochloride NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other naloxone hydrochloride NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
naloxone hydrochloride	Naloxone hydrochloride .4 mg/mL	Injection, SolutionIntramuscular, Intravenous, Subcutaneous	Lifestar Pharma LLC	70756-850	70756-0850-1070756-0850-2570756-0850-82
Naloxone Hydrochloride	Naloxone hydrochloride .4 mg/mL	Injection, SolutionIntramuscular, Intravenous, Subcutaneous	Henry Schein, Inc.	0404-9773	00404-9773-01
Naloxone Hydrochloride	Naloxone hydrochloride .4 mg/mL	InjectionIntramuscular, Intravenous, Subcutaneous	Hikma Pharmaceuticals USA Inc.	0641-6193	00641-6193-10
Naloxone Hydrochloride	Naloxone hydrochloride 4 mg/.1mL	SprayNasal	BluePoint Laboratories	68001-645	68001-0645-45
Naloxone Hydrochloride	Naloxone hydrochloride 4 mg/.1mL	SprayNasal	Strategic Sourcing Services LLC	70677-1283	70677-1283-01
Naloxone Hydrochloride	Naloxone hydrochloride 4 mg/.1mL	SprayNasal	AMERISOURCE BERGEN	46122-812	46122-0812-71
Naloxone Hydrochloride	Naloxone hydrochloride 4 mg/.1mL	Spray, MeteredNasal	Actavis Pharma, Inc.	0591-3871	00591-3871-99
Naloxone Hydrochloride	Naloxone hydrochloride 1 mg/mL	InjectionIntramuscular, Intravenous, Subcutaneous	Par Health USA, LLC	42023-224	42023-0224-01
Naloxone Hydrochloride	Naloxone hydrochloride 4 mg/.1mL	Spray, MeteredNasal	Sportpharm LLC	85766-228	85766-0228-02
Naloxone Hydrochloride	Naloxone hydrochloride 4 mg/.1mL	Spray, MeteredNasal	Teva Pharmaceuticals, Inc.	0480-3478	00480-3478-68

All 78 naloxone hydrochloride NDCs

Other NDCs under ANDA 214785

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 214785
Product	Strength	Form · route	Labeler	Product NDC
naloxone hydrochloride	Naloxone hydrochloride .4 mg/mL	Injection, SolutionIntramuscular, Intravenous, Subcutaneous	Medical Purchasing Solutions, LLC	71872-7297
naloxone hydrochloride	Naloxone hydrochloride .4 mg/mL	Injection, SolutionIntramuscular, Intravenous, Subcutaneous	Baxter Healthcare Corporation	36000-308