NDC codes

FDA NDC Directory
Product NDC (as listed)43066-021Labeler and product segments. Claims need a package NDC.
Product NDC at billing width43066-0021Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
43066-021-104306600211010 BAG in 1 CARTON (43066-021-10) / 200 mL in 1 BAGMarketed from Aug 22, 2020

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Cardene IV
Generic name (nonproprietary)
nicardipine hydrochloride
Active ingredients
Nicardipine hydrochloride — .1 mg/mL
Dosage form
Injection, Solution
Route
Intravenous
Labeler
Baxter Healthcare CorporationNDC labeler code 43066
Product type
Prescription drug
Marketing category
NDA — New Drug ApplicationApplication NDA 019734
Marketing start
Listing expires
Other FDA classes
Calcium Channel Antagonists (Mechanism)Cytochrome P450 2C19 Inhibitors (Mechanism)Cytochrome P450 2C8 Inhibitors (Mechanism)Cytochrome P450 2D6 Inhibitors (Mechanism)Cytochrome P450 3A4 Inhibitors (Mechanism)Dihydropyridines (Chemical structure)
Identifiers
Product ID 43066-021_bf4088a4-3cf9-4963-bfdd-79a641a552d7SPL ID bf4088a4-3cf9-4963-bfdd-79a641a552d7SPL set ID 5499cfac-9147-4d5d-a8cb-f8d64f1481afRxCUI 858599, 858601, 858603, 858605UNII K5BC5011K3
Pharmacologic class
Dihydropyridine Calcium Channel Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N443066002110 followed by a unit qualifier and the quantity

Package 43066-0021-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

• CARDENE I.V. is a calcium channel blocker indicated for the short-term treatment of hypertension in adults when oral therapy is not feasible. ( 1.1 ) 1.1 Hypertension CARDENE I.V. (nicardipine hydrochloride) is indicated in adults for the short-term treatment of hypertension when oral therapy is not feasible or not desirable. For prolonged control of blood pressure, transfer patients to oral medication as soon as their clinical condition permits [see Dosage and Administration (2.1) ].

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 43066-021

What is NDC 43066-021?
43066-021 is the product NDC for Cardene IV (nicardipine hydrochloride), Nicardipine hydrochloride .1 mg/mL injection, solution, listed with the FDA by Baxter Healthcare Corporation. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Cardene IV (Nicardipine hydrochloride).
What is the active ingredient?
Nicardipine hydrochloride.
Who is the labeler?
Baxter Healthcare Corporation, NDC labeler code 43066. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Cardene IV?
6 other product NDCs are listed under this name. See all Cardene IV NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Cardene IV NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .1 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-00943066-0009-10
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .2 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-01643066-0016-10
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .2 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-02443066-0024-10
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .1 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-02643066-0026-10
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .2 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-02843066-0028-10
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride 2.5 mg/10mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-02943066-0029-10

Other NDCs under NDA 019734

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 019734
ProductStrengthForm · routeLabelerProduct NDC
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .1 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-009
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .2 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-016
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .2 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-024
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .1 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-026
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride .2 mg/mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-028
Cardene IVnicardipine hydrochlorideNicardipine hydrochloride 2.5 mg/10mLInjection, SolutionIntravenousBaxter Healthcare Corporation43066-029

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