NDC codes

FDA NDC Directory
Product NDC (as listed)42571-497Labeler and product segments. Claims need a package NDC.
Product NDC at billing width42571-0497Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
42571-497-57425710497571 BOTTLE in 1 CARTON (42571-497-57) / 15 mL in 1 BOTTLEMarketed from Feb 1, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Proparacaine hydrochloride
Generic name (nonproprietary)
proparacaine hydrochloride
Active ingredients
Proparacaine hydrochloride — 5 mg/mL
Dosage form
Solution/ drops
Route
Ophthalmic
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 219294
Marketing start
Listing expires
Other FDA classes
Local Anesthesia (Physiologic effect)
Identifiers
Product ID 42571-497_41be90a9-dfee-6fcc-e063-6394a90a4124SPL ID 41be90a9-dfee-6fcc-e063-6394a90a4124SPL set ID df1af0e8-7d9d-4511-9d86-f0c31a5da2c2RxCUI 1191013UNII U96OL57GOYUPC 0342571497576
Pharmacologic class
Local Anesthetic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Ophthalmic products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N442571049757 followed by a unit qualifier and the quantity

Package 42571-0497-57. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

INDICATIONS AND USAGE Proparacaine Hydrochloride Ophthalmic solution is indicated for topical anesthesia in ophthalmic practice. Representative ophthalmic procedures in which the preparation provides good local anesthesia include measurement of intraocular pressure (tonometry), removal of foreign bodies and sutures from the cornea, conjunctival scraping in diagnosis and gonioscopic examination; it is also indicated for use as a topical anesthetic prior to surgical operations such as cataract extraction.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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