What is NDC 41226-043?

41226-043 is the product NDC for Extra Strength Acetaminophen PM, Acetaminophen 500 mg/1; Diphenhydramine hydrochloride 25 mg/1 tablet, listed with the FDA by Kroger. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Extra Strength Acetaminophen PM (Acetaminophen, Diphenhydramine Hydrochloride).

What is the active ingredient?

Acetaminophen, Diphenhydramine hydrochloride.

Kroger, NDC labeler code 41226. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Extra Strength Acetaminophen PM?

3 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Extra Strength Acetaminophen PM NDC 41226-043

NDC codes

FDA NDC Directory

Product NDC (as listed)41226-043Labeler and product segments. Claims need a package NDC.

Product NDC at billing width41226-0043Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
41226-043-20	4122600432041226004320	2 BOTTLE in 1 CARTON (41226-043-20) / 100 TABLET in 1 BOTTLE (41226-043-01)Marketed from Sep 15, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Extra Strength Acetaminophen PM
Generic name (nonproprietary): acetaminophen, diphenhydramine hydrochloride
Active ingredients: Acetaminophen — 500 mg/1Diphenhydramine hydrochloride — 25 mg/1
Dosage form: Tablet
Route: Oral
Labeler: KrogerNDC labeler code 41226
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 013
Marketing start: Sep 15, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Histamine H1 Receptor Antagonists (Mechanism)
Identifiers: Product ID 41226-043_5a1959e3-ff81-a0b4-e063-6394a90a356aSPL ID 5a1959e3-ff81-a0b4-e063-6394a90a356a
Pharmacologic class: Histamine-1 Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N441226004320 followed by a unit qualifier and the quantity

Package 41226-0043-20. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 41226-043

What is NDC 41226-043?: 41226-043 is the product NDC for Extra Strength Acetaminophen PM, Acetaminophen 500 mg/1; Diphenhydramine hydrochloride 25 mg/1 tablet, listed with the FDA by Kroger. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Extra Strength Acetaminophen PM (Acetaminophen, Diphenhydramine Hydrochloride).
What is the active ingredient?: Acetaminophen, Diphenhydramine hydrochloride.
Who is the labeler?: Kroger, NDC labeler code 41226. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Extra Strength Acetaminophen PM?: 3 other product NDCs are listed under this name. See all Extra Strength Acetaminophen PM NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Extra Strength Acetaminophen PM NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Extra Strength Acetaminophen PMacetaminophen, diphenhydramine	Acetaminophen 500 mg/1; Diphenhydramine hydrochloride 25 mg/1	TabletOral	BJWC (Berkley & Jensen / BJ's)	68391-430	68391-0430-50
Extra strength Acetaminophen PMacetaminophen 500mg/ diphenhydramine hcl 25mg	Diphenhydramine hydrochloride 25 mg/1; Acetaminophen 500 mg/1	TabletOral	TIME CAP LABS INC	49483-430	49483-0430-40
Extra Strength Acetaminophen PMacetaminophen and diphenhydramine hydrochloride	Acetaminophen 500 mg/1; Diphenhydramine hydrochloride 25 mg/1	TabletOral	KROGER COMPANY	30142-755	30142-0755-0130142-0755-0530142-0755-20

Other NDCs under M 013

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 013
Product	Strength	Form · route	Labeler	Product NDC
Acetaminophen	Acetaminophen 500 mg/1	Tablet, CoatedOral	COSTCO WHOLESALE CORPORATION	63981-019
Extra Strength Pain Releifacetaminophen	Acetaminophen 500 mg/1	Tablet, Film coatedOral	Strategic Sourcing Services, LLC	70677-1242
Aspirin 81 mgaspirin	Aspirin 81 mg/1	Tablet, Delayed releaseOral	H E B	37808-600
TYLENOL Extra Strengthacetaminophen	Acetaminophen 500 mg/1	Tablet, Film coatedOral	Morning Star OTC	53209-1001
Extra Strength Pain Relieveracetaminophen tablets 500 mg	Acetaminophen 500 mg/1	TabletOral	WALGREENS	0363-0669
Pain Relieveracetaminophen capsules 500mg (minis-red opaque)	Acetaminophen 500 mg/1	Capsule, Liquid filledOral	Walgreens	0363-6684
Mommys Bliss Childrens Pain and Feveracetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	Mom Enterprises, LLC.	71444-793
Childrens Pain and Feveracetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	CVS Pharmacy	59779-126
Good Neighbor Pharmacy childrens pain and feveracetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	Amerisource Bergen	46122-211
Acetaminophen	Acetaminophen 160 mg/5mL	LiquidOral	A-S Medication Solutions	50090-6059
Members Mark Acetaminophenacetaminophen	Acetaminophen 500 mg/1	TabletOral	Sam's West Inc	68196-606
Mommys Bliss Infants Pain and Feveracetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	Mom Enterprises, LLC.	71444-893
Thompson Extra Strength Non-Aspirinacetaminophen	Acetaminophen 500 mg/1	TabletOral	Thompson	73408-174
Aspirin 81 mg Low Doseaspirin	Aspirin 81 mg/1	Tablet, Delayed releaseOral	CHAIN DRUG MARKETING ASSOCIATION, INC.	83324-089
Acetaminophen	Acetaminophen 500 mg/1	TabletOral	ASCLEMED USA INC.	87063-222
Pain Relief Aspirin Low Doseaspirin	Aspirin 81 mg/1	Tablet, Delayed releaseOral	Rite Aid Corporation	11822-0600
equate pain and fever childrensacetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	Wal-Mart Stores Inc	49035-042
Pain and Fever Childrensacetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	P & L Development, LLC	49580-0282
Dye Free Pain and Fever Childrensacetaminophen	Acetaminophen 160 mg/5mL	SuspensionOral	Walgreens	0363-0285
Pain Reliever Extra Strengthacetaminophen	Acetaminophen 500 mg/1	Tablet, CoatedOral	Walgreen Company	0363-0519

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