What is NDC 21130-789?

21130-789 is the product NDC for Signature Care Hemorrhoidal, Petrolatum 749 mg/g + 2 more ingredients ointment, listed with the FDA by Better Living Brands, LLC. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Signature Care Hemorrhoidal (Mineral oil, Petrolatum, and Phenylephrine HCI).

What is the active ingredient?

Petrolatum, Phenylephrine hydrochloride, Mineral oil.

Better Living Brands, LLC, NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Signature Care Hemorrhoidal?

2 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Signature Care Hemorrhoidal NDC 21130-789

NDC codes

FDA NDC Directory

Product NDC (as listed)21130-789Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21130-0789Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21130-789-14	2113007891421130078914	1 TUBE in 1 CARTON (21130-789-14) / 28 g in 1 TUBEMarketed from Jan 21, 2016

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Signature Care Hemorrhoidal
Generic name (nonproprietary): mineral oil, petrolatum, and phenylephrine hci
Active ingredients: Petrolatum — 749 mg/gPhenylephrine hydrochloride — 2.5 mg/gMineral oil — 140 mg/g
Dosage form: Ointment
Route: Topical
Labeler: Better Living Brands, LLCNDC labeler code 21130
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 015
Marketing start: Jan 20, 2016
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic alpha1-Agonists (Mechanism)
Identifiers: Product ID 21130-789_4a197084-aa10-02ef-e063-6394a90a1e46SPL ID 4a197084-aa10-02ef-e063-6394a90a1e46SPL set ID 3c8b43f3-6e1e-499e-ba71-ffdf836f6743RxCUI 1372298UNII 4T6H12BN9U, 04JA59TNSJ, T5L8T28FGPUPC 0321130789826
Pharmacologic class: alpha-1 Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421130078914 followed by a unit qualifier and the quantity

Package 21130-0789-14. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Feb 5, 2026.

Indications (excerpt from the label)

Directions adults: when practical, cleanse the affected area by patting or blotting with an appropriate cleansing wipe. Gently dry by patting or blotting with a tissue or a soft cloth before applying ointment. when first opening the tube, puncture foil seal with top end of cap apply to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement interacetal use: remove cover from applicator, attach applicator to tube, lubricate applicator well and gently insert applicator into thoroughly cleanse applicator after each use and replace cover also apply ointment to external area regular use provides continual therapy for relief of symptoms children unde…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21130-789

What is NDC 21130-789?: 21130-789 is the product NDC for Signature Care Hemorrhoidal, Petrolatum 749 mg/g + 2 more ingredients ointment, listed with the FDA by Better Living Brands, LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Signature Care Hemorrhoidal (Mineral oil, Petrolatum, and Phenylephrine HCI).
What is the active ingredient?: Petrolatum, Phenylephrine hydrochloride, Mineral oil.
Who is the labeler?: Better Living Brands, LLC, NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Signature Care Hemorrhoidal?: 2 other product NDCs are listed under this name. See all Signature Care Hemorrhoidal NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Signature Care Hemorrhoidal NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
signature care hemorrhoidalmineral oil, petrolatum, phenylephrine hcl	Mineral oil 14 g/100g + 2 more ingredients	OintmentRectal	Safeway	21130-577	21130-0577-16
Signature Care Hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Safeway	21130-628	21130-0628-62

Other NDCs under M 015

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 015
Product	Strength	Form · route	Labeler	Product NDC
Hempvana Maximum Strength Pain Relief Topical Anesthetic Platinumlidocaine 5%	Lidocaine 5 g/100g	CreamTopical	Telebrands Corp	73287-040
Nupharmisto NumbMD LIDOCAINE cream anorectal (hemorrhoidal)lidocaine cream anorectal	Lidocaine 4 g/80g	CreamTopical	EveryMarket Inc	85833-002
Lidonumblidocaine 5%	Lidocaine .05 g/g	CreamTopical	Rising Pharma Holdings, Inc.	57237-353
Exchange Select Hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Army & Air Force Exchange Service	55301-279
Preparation H Medicated Wipeswitch hazel	Witch hazel 5 g/1	ClothTopical	Haleon US Holdings LLC	0573-0557
Lidocaine anorectal creamlidocaine 5%	Lidocaine 5 g/100g	CreamTopical	EveryMarket Inc	85833-001
hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Kroger Company	30142-279
hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Meijer Distribution Inc	41250-279
hemorrhoidal maximum strength pain reliefglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	Kroger Company	30142-944
Oxifylidocaine 5%	Lidocaine 50 mg/g	CreamTopical	Weeks & Leo Compnay, INC.	11383-331
hemorrhoidalglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	Publix Super Markets Inc	56062-944
Black Label B Numblidocaine hydrochloride	Lidocaine hydrochloride 5 g/100mL	SprayTopical	SCALP TECH INC	82617-103
hemorrhoidalmineral oil, petrolatum, phenylephrine hcl	Mineral oil 14 g/100g + 2 more ingredients	OintmentRectal	Amazon.com Services LLC	72288-767
The Solutionlidocaine hydrochloride, epinephrine hydrochloride	Lidocaine hydrochloride 5 g/100mL; Epinephrine hydrochloride .01 g/100mL	SprayTopical	SCALP TECH INC	82617-101
Good Sense Hemorrhoidal Maximum Strength Pain Reliefglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	L. Perrigo Company	0113-0944
The Solution 2.0lidocaine	Lidocaine hydrochloride 5 g/100mL	SprayTopical	SCALP TECH INC	82617-102
Equaline Hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	United Natural Foods, Inc. dba UNFI	41163-279
Walgreens Moisture Barriermenthol, and zinc oxide	Menthol .44 g/100g; Zinc oxide 20.6 g/100g	CreamTopical	Walgreen Company	0363-3680
The Solu Tionlidocaine hydrochloride and epinephrine hydrochloride	Lidocaine hydrochloride 5 g/100mL; Epinephrine hydrochloride .01 g/100mL	Aerosol, FoamTopical	SCALP TECH INC	82617-110
Maximum Strength Hemorrhoidal Cream with Aloeglycerin, phenylephine hci, pramoxine hci, petrolatum	White petrolatum 15 g/100g + 3 more ingredients	CreamTopical	Chain Drug Marketing Association	83324-330

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