Adapalene NDC 21130-754

NDC codes

FDA NDC Directory

Product NDC (as listed)21130-754Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21130-0754Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21130-754-05	21130075405	1 TUBE in 1 CARTON (21130-754-05) / 15 g in 1 TUBEMarketed from Jan 31, 2024

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Adapalene
Generic name (nonproprietary): adapalene
Active ingredients: Adapalene — 1 mg/g
Dosage form: Gel
Route: Topical
Labeler: Safeway, Inc.
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 090962
Marketing start: Jan 31, 2024
Listing expires: Dec 31, 2027
Other FDA classes: Retinoids (Chemical structure)
Identifiers: Product ID 21130-754_d22d813a-9035-4065-9f49-51b778527c72SPL ID d22d813a-9035-4065-9f49-51b778527c72SPL set ID a9816181-d643-4579-8b12-3927120dc627RxCUI 307731UNII 1L4806J2QFUPC 0321130129318
Pharmacologic class: Retinoid

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Topical products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421130075405 followed by a unit qualifier and the quantity

Package 21130-0754-05. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 18, 2026.

Indications (excerpt from the label)

Use For the treatment of acne

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 090962

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 090962
Product	Strength	Form · route	Labeler	Product NDC
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	The Kroger Co.	30142-542
Adapalene	Adapalene 1 mg/g	GelTopical	YYBA CORP	73581-215
Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatmentadapalene	Adapalene 1 mg/g	GelTopical	Kenvue Brands LLC	69968-0945
Adapalene	Adapalene 1 mg/g	GelTopical	CVS PHARMACY, INC	51316-114
Adapalene	Adapalene 1 mg/g	GelTopical	The Kroger Co.	30142-725
Neutrogena Evenly Clear Retinoid Adapalene Gel 0.1% Acne Treatmentadapalene	Adapalene 1 mg/g	GelTopical	Kenvue Brands LLC	69968-1004
Adapalene	Adapalene 1 mg/g	GelTopical	Topco Associates	76162-114
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	CVS PHARMACY, INC	51316-219
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	Topco Associates	76162-221
Adapalene	Adapalene 1 mg/g	GelTopical	Walgreens	0363-1401
Adapalene	Adapalene 1 mg/g	GelTopical	Meijer Distribution Inc.	79481-1140
Adapalene Paraben Freeadapalene	Adapalene 1 mg/g	GelTopical	Meijer Distribution Inc.	79481-2210
Neutrogena Adapalene 0.1% Acne Treatmentadapalene	Adapalene 1 mg/g	GelTopical	Kenvue Brands LLC	69968-0826
Adapalene	Adapalene 1 mg/g	GelTopical	P & L Development, LLC	59726-114
Adapalene	Adapalene 1 mg/g	GelTopical	Walgreens	0363-4110