What is NDC 21130-182?

21130-182 is the product NDC for SIGNATURE CARE Regular Strength (bismuth subsalicylate), Bismuth subsalicylate 525 mg/30mL suspension, listed with the FDA by SAFEWAY. It has 2 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

SIGNATURE CARE Regular Strength (Bismuth subsalicylate).

SAFEWAY, NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for SIGNATURE CARE Regular Strength?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

SIGNATURE CARE Regular Strength NDC 21130-182

NDC codes

FDA NDC Directory

Product NDC (as listed)21130-182Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21130-0182Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21130-182-12	21130018212	354 mL in 1 BOTTLE (21130-182-12)Marketed from Feb 2, 2026
21130-182-16	21130018216	473 mL in 1 BOTTLE (21130-182-16)Marketed from Feb 2, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): SIGNATURE CARE Regular StrengthSuffix: Regular Strength
Generic name (nonproprietary): bismuth subsalicylate
Active ingredients: Bismuth subsalicylate — 525 mg/30mL
Dosage form: Suspension
Route: Oral
Labeler: SAFEWAYNDC labeler code 21130
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 008
Marketing start: Feb 2, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Bismuth (Chemical structure)
Identifiers: Product ID 21130-182_b4643d99-90ce-4f00-a61a-a5371fe0f424SPL ID b4643d99-90ce-4f00-a61a-a5371fe0f424SPL set ID b4643d99-90ce-4f00-a61a-a5371fe0f424RxCUI 308762UNII 62TEY51RR1UPC 0321130789666
Pharmacologic class: Bismuth

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421130018212 followed by a unit qualifier and the quantity

Package 21130-0182-12. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Feb 20, 2026.

Indications (excerpt from the label)

Uses relieves ▪ travelers’ diarrhea ▪ diarrhea ▪ upset stomach due to overindulgence in food and drink, including: ▪ heartburn ▪ indigestion ▪ nausea ▪ gas ▪ belching ▪ fullness

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 21130-182

What is NDC 21130-182?: 21130-182 is the product NDC for SIGNATURE CARE Regular Strength (bismuth subsalicylate), Bismuth subsalicylate 525 mg/30mL suspension, listed with the FDA by SAFEWAY. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: SIGNATURE CARE Regular Strength (Bismuth subsalicylate).
What is the active ingredient?: Bismuth subsalicylate.
Who is the labeler?: SAFEWAY, NDC labeler code 21130. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for SIGNATURE CARE Regular Strength?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under M 008

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 008
Product	Strength	Form · route	Labeler	Product NDC
FEVIA Diarrhea Controlbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	Capsule, Liquid filledOral	VIVUNT PHARMA LLC	82706-028
Topcare Stomach Relief cherrybismuth subsalicylate	Bismuth subsalicylate 525 mg/30mL	LiquidOral	Topco Associates, LLC	36800-769
Pep Tumbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	Tablet, ChewableOral	First Aid Direct	53117-046
Stomach Relief Regular Strengthbismuth subsalicylate	Bismuth subsalicylate 525 mg/30mL	LiquidOral	P & L Development, LLC	49580-0624
Stomach Relief Regular Strengthbismuth subsalicylate	Bismuth subsalicylate 525 mg/30mL	LiquidOral	P & L Development, LLC	49580-0724
Regular Strength Stomach Reliefbismuth subsalicylate	Bismuth subsalicylate 525 mg/30mL	SuspensionOral	Walmart Inc.	79903-443
TopCare Regular Strengthbismuth subsalicylate	Bismuth subsalicylate 525 mg/30mL	SuspensionOral	TOPCO ASSOCIATES LLC	36800-661
Walgreen Ultra Strength Pink Bismuthbismuth subsalicylate	Bismuth subsalicylate 525 mg/15mL	SuspensionOral	WALGREENS CO.	0363-7070
WinCo FOODS Stomach Reliefbismuth subsalicylate	Bismuth subsalicylate 525 mg/30mL	SuspensionOral	WINCO FOODS	67091-362
Stomach Relief Ultra Strengthbismuth subsalicylate	Bismuth subsalicylate 525 mg/15mL	LiquidOral	P & L Development, LLC	49580-0842
WinCo FOODS Ultra Strength Stomach Reliefbismuth subsalicylate	Bismuth subsalicylate 525 mg/15mL	SuspensionOral	WINCO FOODS	67091-363
WinCo FOODS Stomach Reliefbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	Tablet, ChewableOral	WINCO FOODS LLC	67091-364
Kaopectate Peppermint Flavor Anti Diarrhealbismuth subsalicylate	Bismuth subsalicylate 262 mg/15mL	LiquidOral	Kramer Laboratories	55505-199
meijer stomach reliefbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	TabletOral	Meijer Distribution Inc	41250-324
Thompson Chewable Bismuth Tabsbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	Tablet, ChewableOral	Thompson Safety LLC	73408-407
Topco Stomach Reliefbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	TabletOral	Topco Associates, LLC	36800-104
Kaopectatebismuth subsalicylate	Bismuth subsalicylate 262 mg/1	Tablet, CoatedOral	Kramer Laboratories	55505-197
5-Symptom Digestive Reliefbismuth subsalicylate	Bismuth subsalicylate 262 mg/1	TabletOral	TARGET CORPORATION	11673-880
Kaopectate Vanilla Flavor Anti Diarrhealbismuth subsalicylate	Bismuth subsalicylate 262 mg/15mL	LiquidOral	Kramer Laboratories	55505-198
QC Anti Diarrheal Vanilla Regular Flavorbismuth subsalicylate	Bismuth subsalicylate 262 mg/15mL	SuspensionOral	QUALITY CHOICE (CHAIN DRUG MARKETING ASSOCIATION)	63868-339

Showing 20 of 40.

SIGNATURE CARE Regular Strength (Bismuth subsalicylate) NDC 21130-182