NDC 21130-105

NDC codes

FDA NDC Directory

Product NDC (as listed)21130-105Labeler and product segments. Claims need a package NDC.

Product NDC at billing width21130-0105Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
21130-105-02	21130010502	1 BOTTLE, PLASTIC in 1 CARTON (21130-105-02) / 2.5 mL in 1 BOTTLE, PLASTICMarketed from Jun 25, 2021

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Olopatadine Hydrochloride Ophthalmic Solution
Generic name (nonproprietary): olopatadine hydrochloride ophthalmic
Active ingredients: Olopatadine hydrochloride — 2 mg/mL
Dosage form: Solution
Route: Ophthalmic
Labeler: Albertsons Companies
Product type: Over-the-counter drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 209752
Marketing start: Jun 25, 2021
Listing expires: Dec 31, 2026
Other FDA classes: Decreased Histamine Release (Physiologic effect)Histamine H1 Receptor Antagonists (Mechanism)
Identifiers: Product ID 21130-105_ac0a51c9-185a-9d58-cb21-ee5b6a1134d6SPL ID ac0a51c9-185a-9d58-cb21-ee5b6a1134d6SPL set ID 685192af-d729-3066-5825-6d0e03ce787eRxCUI 1111343UNII 2XG66W44KF
Pharmacologic class: Histamine-1 Receptor Antagonist; Histamine-1 Receptor Inhibitor; Mast Cell Stabilizer

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Ophthalmic products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N421130010502 followed by a unit qualifier and the quantity

Package 21130-0105-02. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 12, 2025.

Indications (excerpt from the label)

USE temporarily relieves itchy eyes due to pollen, ragweed, grass, animal hair and dander

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under ANDA 209752

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 209752
Product	Strength	Form · route	Labeler	Product NDC
CVS Eye Allergy Itch Relief Once Dailyolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	CVS Health Corp	69842-269
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Gland Pharma Limited	68083-231
Eye Allergy Itch Reliefolopatadine hcl	Olopatadine hydrochloride 2 mg/mL	Solution/ dropsOphthalmic	CARDINAL HEALTH 110, LLC. DBA LEADER	70000-0053
Eye Allergy Itch Relief Once Daily Reliefolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Strategic Sourcing Services LLC	70677-1155
Olopatadine Hydrochloride	Olopatadine hydrochloride 2 mg/mL	Solution/ dropsOphthalmic	Rugby Laboratories	0536-1307
Once Daily Reliefolopatadine hydrochloride ophthalmic solution	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	H E B	37808-045
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Rite Aid Corporation	11822-9975
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Walgreens Company	0363-7131
Olopatadine Hydrochloride Ophthalmic Solution Once Dailyolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	DOLGENCORP, LLC	55910-137
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Chain Drug Marketing Association INC	83324-120
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Dr. Reddy's Laboratories Inc.	43598-764
Allergy Relief Eye Dropsolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	CVS Pharmacy	51316-675
Eye Allergy Itch Relief Once Daily Reliefolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Dr. Reddy's Laboratories Inc.	43598-827
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Chain Drug Marketing Association INC	63868-821
Olopatadine Hydrochloride Ophthalmic Solutionolopatadine hydrochloride ophthalmic	Olopatadine hydrochloride 2 mg/mL	SolutionOphthalmic	Target Corporation	11673-688

Olopatadine Hydrochloride Ophthalmic Solution NDC 21130-105