Emerphed PFS (ephedrine sulfate) NDC 14789-251

NDC codes

FDA NDC Directory

Product NDC (as listed)14789-251Labeler and product segments. Claims need a package NDC.

Product NDC at billing width14789-0251Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
14789-251-10	14789025110	10 SYRINGE in 1 CARTON (14789-251-10) / 5 mL in 1 SYRINGE (14789-251-09)Marketed from Mar 1, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Emerphed PFSSuffix: PFS
Generic name (nonproprietary): ephedrine sulfate
Active ingredients: Ephedrine sulfate — 5 mg/mL
Dosage form: Injection
Route: Intravenous
Labeler: Nexus Pharmaceuticals, LLC
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 213407
Marketing start: Mar 1, 2023
Listing expires: Dec 31, 2026
Other FDA classes: Adrenergic alpha-Agonists (Mechanism)Adrenergic beta-Agonists (Mechanism)Increased Norepinephrine Activity (Physiologic effect)
Identifiers: Product ID 14789-251_5064287a-af00-4516-a8a3-f430f176e06eSPL ID 5064287a-af00-4516-a8a3-f430f176e06eSPL set ID 14601778-93ac-43ec-b66b-5a942317133fRxCUI 2586841, 2631015, 2631017, 2631018UNII U6X61U5ZEG
Pharmacologic class: Norepinephrine Releasing Agent; alpha-Adrenergic Agonist; beta-Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N414789025110 followed by a unit qualifier and the quantity

Package 14789-0251-10. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Sep 16, 2024.

Indications (excerpt from the label)

1. INDICATIONS AND USAGE EMERPHED and EMERPHED-PFS is indicated for the treatment of clinically important hypotension occurring in the setting of anesthesia. EMERPHED and EMERPHED-PFS is an alpha- and beta- adrenergic agonist and a norepinephrine-releasing agent that is indicated for the treatment of clinically important hypotension occurring in the setting of anesthesia. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 213407

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 213407
Product	Strength	Form · route	Labeler	Product NDC
Emerphedephedrine sulfate	Ephedrine sulfate 5 mg/mL	InjectionIntravenous	Nexus Pharamaceuticals Inc.	14789-250
Emerphed PFSephedrine sulfate	Ephedrine sulfate 5 mg/mL	InjectionIntravenous	Nexus Pharmaceuticals, LLC	14789-252